Design Concepts in Nutritional Epidemiology / Edition 1

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Overview


This book focuses on the key issues of design and analysis in studies which aim to relate measures of nutritional exposure to disease outcome. The first section discusses how to identify the appropriate measures of exposure and outcome in order to formulate a clear research hypothesis, including the question of power and sample size. This is followed by a detailed discussion of how to measure the exposures and outcomes with a desired degree of accuracy. Particular emphasis is placed on the identification of measurement error and confounding factors, and how to cope with their influence on the observed relationships. The final section addresses the problem of design and interpretation that arise in epidemiological studies - ecological, case control, cohort, and experimental - which include measures of nutritional exposure. The need for this book arises because of the complexity of nutritional exposures. By learning how to identify relevant measures of nutritional exposure and measure them correctly in epidemiological studies, we improve our ability to assess the role of nutrition in disease etiology.

The book contains black-and-white illustrations.

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Editorial Reviews

Diane S. Lauderdale
This book presents 16 chapters by different contributors covering the principles of epidemiologic research in general and the design, measurement, and analysis issues specific to studies incorporating nutritional data. It is the second edition of a 1991 publication. "The purpose is to present a comprehensive guide, text, and reference to research methods in nutritional epidemiology. This second edition presents recent advances in nutritional assessment and gene-nutrient interactions, as well as an expanded treatment of the non-nutritional components of epidemiologic study design. "The book is written for nutritionists and epidemiologists, but would also be of value to any researcher working with population-based or clinical studies incorporating nutritional assessment. Chapters on covariate measurement errors in nutritional epidemiology, biochemical markers, and validity of dietary assessment are particularly useful. Although articles are current and thorough, no particular background is assumed. Contributors are uniformly knowledgeable. "The organization of the book lends itself to use either as a text or a reference. The substantial reference lists accompanying each chapter generally include many publications which appeared after the first edition. "The majority of the contributors are British, with others from the Netherlands, Australia, and the United States. Coverage includes research from throughout the world. The greater emphasis on international data is one difference between this volume and Walter Willett's Nutritional Epidemiology. This book, indeed, focuses on methodology and does not review substantive research on the role of diet in specificdiseases. About one-quarter of the book concerns basic biostatistical and epidemiologic topics. While these chapters are competent, they cannot substitute for full introductory texts. The quality of the chapters is consistently high; the reader is occasionally referred from one chapter to another, a sign of a well-edited compilation.
From The Critics
Reviewer: Diane S. Lauderdale, PhD (University of Chicago Pritzker School of Medicine)
Description: This book presents 16 chapters by different contributors covering the principles of epidemiologic research in general and the design, measurement, and analysis issues specific to studies incorporating nutritional data. It is the second edition of a 1991 publication.
Purpose: The purpose is to present a comprehensive guide, text, and reference to research methods in nutritional epidemiology. This second edition presents recent advances in nutritional assessment and gene-nutrient interactions, as well as an expanded treatment of the non-nutritional components of epidemiologic study design.
Audience: The book is written for nutritionists and epidemiologists, but would also be of value to any researcher working with population-based or clinical studies incorporating nutritional assessment. Chapters on covariate measurement errors in nutritional epidemiology, biochemical markers, and validity of dietary assessment are particularly useful. Although articles are current and thorough, no particular background is assumed. Contributors are uniformly knowledgeable.
Features: The organization of the book lends itself to use either as a text or a reference. The substantial reference lists accompanying each chapter generally include many publications which appeared after the first edition.
Assessment: The majority of the contributors are British, with others from the Netherlands, Australia, and the United States. Coverage includes research from throughout the world. The greater emphasis on international data is one difference between this volume and Walter Willett's Nutritional Epidemiology. This book, indeed, focuses on methodology and does not review substantive research on the role of diet in specific diseases. About one-quarter of the book concerns basic biostatistical and epidemiologic topics. While these chapters are competent, they cannot substitute for full introductory texts. The quality of the chapters is consistently high; the reader is occasionally referred from one chapter to another, a sign of a well-edited compilation.

3 Stars from Doody
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Product Details

  • ISBN-13: 9780192618733
  • Publisher: Oxford University Press, USA
  • Publication date: 1/28/1991
  • Series: Oxford Medical Publications Series
  • Edition description: Older Edition
  • Edition number: 1
  • Pages: 432
  • Product dimensions: 6.38 (w) x 9.50 (h) x 1.16 (d)

Table of Contents

List of contributors
Introduction
Pt. A The scientific concepts underlying study design
1 Overview of the principles of nutritional epidemiology 3
2 Design, planning, and evaluation of nutritional epidemiological studies 39
3 Sampling, study size, and power 64
4 Covariate measurement errors in nutritional epidemiology: effects and remedies 87
Pt. B The measurement of exposure and outcome
5 Food consumption, nutrient intake, and the use of food composition tables 107
6 Assessment of food consumption and nutrient intake 123
7 Biochemical markers of nutrient intake 170
8 The validation of dietary assessment 241
9 Socio-demographic and psycho-social variables 273
10 Anthropometric measures 289
11 Gene-nutrient interactions in nutritional epidemiology 312
Pt. C The design of nutritional epidemiological studies
12 Ecological studies 341
13 Cross-sectional studies 369
14 Cohort studies 383
15 Case-control studies 399
16 Experimental studies: clinical trials, field trials, community trials, and intervention studies 415
Index 441
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