Design Principles for the Immune System and Other Distributed Autonomous Systems / Edition 1

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Oxford, England 2001 Trade paperback New. BRAND NEW; gift quality. Trade paperback (US). Glued binding. 428 p. Contains: Illustrations. Santa Fe Institute Studies in the Science ... of Complexity. Audience: General/trade. Read more Show Less

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Overview

Design Principles for the Immune System and Other Distributed Autonomous Systems is the first book to examine the inner workings of such a variety of distributed autonomous systems—from insect colonies to high level computer programs to the immune system. It offers insight into the fascinating world of these systems that emerge from the interactions of seemingly autonomous components and brings us up-to-date on the state of research in these areas.
Using the immune system and certain aspects of its functions as a primary model, this book examines many of the most interesting and troubling questions posed by complex systems. How do systems choose the right set of agents to perform appropriate actions with appropriate intensities at appropriate times? How in the immune system, ant colonies and metabolic networks does the diffusion and binding of a large variety of chemicals to their receptors permit coordination of system action? What advantages drive the various systems to complexity, and by what mechanisms do the systems cope with the tendency toward unwieldiness and randomness of large complex systems?

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Editorial Reviews

Booknews
Though the immune system is most thoroughly discussed, the contributors<-->biological, physical, and computer scientists from around the world<-->also consider metabolism and ant colonies as other examples of complex, distributed, autonomous systems, and suggest how research findings about biological systems can be applied to computer science. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Product Details

Table of Contents

Preface
Pt. I An Overview of Immunology
1 Introduction to the Immune System 3
Pt. II Case Studies in Immune Complexity: Experiments
2 Cytokines: A Common Signaling System for Cell Growth, Inflammation, Immunity, and Differentiation 29
3 Th1/Th2 Effector Choice in the Immune System: A Developmental Program Influenced by Cytokine Signals 79
4 Oral Tolerance 95
Pt. III Design Principles for the Immune System
5 An Introduction to Immuno-ecology and Immuno-informatics 125
6 The Creation of Immune Specificity 151
7 Diversity in the Immune System 161
8 T Cells Obey the Tenets of Signal Detection Theory 185
9 Diffuse Feedback from a Diffuse Informational Network: In the Immune System and Other Distributed Autonomous Systems 203
10 Multistep Navigation and the Combinatorial Control of Cell Positioning: A General Model for Generation of Living Structure Based on Studies of Immune Cell Trafficking 227
11 Distributed, Anarchic Immune Organization: Semi-autonomous Golems at Work 241
Pt. IV Biochemical Systems
12 New Approaches to Complex Chemical Reaction Mechanisms 261
Pt. V Social Insects
13 Control Mechanisms for Distributed Autonomous Systems: Insights from the Social Insects 281
14 Task Allocation in Ant Colonies 293
Pt. VI Applications to Computer Science
15 Biologically Motivated Distributed Designs for Adaptive Knowledge Management 305
16 Analogy Making as a Complex Adaptive System 335
17 Immunology as Information Processing 361
Index 389
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