Designing Our Descendants: The Promises and Perils of Genetic Modifications [NOOK Book]

Overview

The Human Genome Project, discoveries in molecular biology, and new reproductive technologies have advanced our understanding of how genetic science may be used to treat persons with genetic disorders. Greater knowledge may also make possible genetic interventions to "enhance" normal human characteristics, such as height, hair or eye color, strength, or memory, as well as the transmittal of such modifications to future generations. The prospect of inheritable genetic modifications, or IGMs, whether for ...

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Designing Our Descendants: The Promises and Perils of Genetic Modifications

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Overview

The Human Genome Project, discoveries in molecular biology, and new reproductive technologies have advanced our understanding of how genetic science may be used to treat persons with genetic disorders. Greater knowledge may also make possible genetic interventions to "enhance" normal human characteristics, such as height, hair or eye color, strength, or memory, as well as the transmittal of such modifications to future generations. The prospect of inheritable genetic modifications, or IGMs, whether for therapeutic or enhancement purposes, raises complex scientific, ethical, and regulatory issues.

Designing Our Descendants presents twenty essays by physicians, scientists, philosophers, theologians, lawyers, and policy analysts addressing these issues from diverse perspectives. In three sections, the authors discuss the short- and long-term scientific feasibility of IGM technology; ethical and religious issues related to safety, justice, morality, reproductive rights, and enhancement; and regulatory issues including the necessity of public input and oversight and the influence of commercialization. Their goal is to open a dialogue engaging not only scholars and scientists but also government officials and concerned citizens. The authors conclude that while IGM cannot be carried out safely and responsibly on humans utilizing current methods, it is important to begin public discussion now to determine whether, and if so how, to proceed.

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What People Are Saying

Thomas H. Murray

This is the product of a multi-year effort at mutual enlightenment and interdisciplinary analysis, not merely a compilation of individually written papers. It should become the leading volume on human genetic modification.

Thomas H. Murray, President, The Hastings Center

Eric M. Meslin

An original and important contribution to the bioethics, genetics, and public policy literature by an impressive group of scholars from across the disciplines.

Eric M. Meslin, Indiana University

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Product Details

  • ISBN-13: 9780801881299
  • Publisher: Johns Hopkins University Press
  • Publication date: 12/1/2004
  • Sold by: Barnes & Noble
  • Format: eBook
  • Pages: 384
  • File size: 3 MB

Meet the Author

Audrey R. Chapman is director of the Science and Human Rights Program and senior associate for ethics in the Dialogue on Science, Ethics, and Religion at the American Association for the Advancement of Science. Mark S. Frankel is the director of the Scientific Freedom, Responsibility, and Law Program at American Association for the Advancement of Science.

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Table of Contents


Contents:PART I: Introduction 1. Framing the Issues

Audrey R. Chapman and Mark S. Frankel2. Germ-Line Dancing: Definitional Considerations for Policy Makers

Eric Juengst and Erik ParensPART II: Scientific Considerations3. Approaches to Gene Tranfer to the Mammalian Germ Line

Theodore Friedmann4. Scientific Methodologies to Facilitate Inheritable Genetic Modifcations in Humans

Bhavani G. Pathak5. Germ-Line Modification in Clinical Medicine: Is There a Case for Intentional or Unintended Germ-Line Changes?

R. Michael Blaese6. Gene Repair, Genomics, and Human Germ-Line Modification

Kenneth W. Culver7. Germ-Line Gene Therapy: CanWe Do It, Do We Need It, Where Do We Start, and Where Might It Lead?

Christopher H. Evans

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Sort by: Showing all of 2 Customer Reviews
  • Anonymous

    Posted November 23, 2005

    Good... If you know your biology, an Oklahoma State University Perspective

    I had the joy of reading this book for my composition class at Oklahoma State University. The book is very nicely proportioned and quite informative however, it has some minor drawbacks. The entire book (science section especially) is mired in heavily scientific verbiage. While this was not bad enough to make me dislike the book, it is unfortunate that as a science major I was still constantly reaching for my biology book to understand the chapters. Furthermore, I was also forced to review cellular theory to fully receive the book's intended effect. I recomend this book highly, just heed my warning about the terminology. The book's excellent organization and relevance to the topic help to make up for the fact that it would be a nightmare for a non-science lover.

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  • Anonymous

    Posted April 17, 2009

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