Designing Randomised Trials in Health, Education and the Social Sciences: An Introduction

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Policy makers are increasingly demanding evidence from randomized trials. The book focuses on the design of rigorous trials rather than their statistical underpinnings or analyses. Consequently, statistical theory is absent and statistical methods are minimal. Few other texts go into such detailed description about randomization procedures and different trial designs within the same volume. The book has chapters on: pragmatic designs; placebo designs; preference approaches; unequal allocation; economics; analytical approaches; randomization methods.

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Product Details

  • ISBN-13: 9780230537361
  • Publisher: Palgrave Macmillan
  • Publication date: 5/13/2008
  • Edition description: First Edition
  • Pages: 256
  • Product dimensions: 5.40 (w) x 8.40 (h) x 0.60 (d)

Meet the Author

DAVID J. TORGERSON is Director of York Trials Unit, University of York, UK. He has published extensively on randomised trial design and has worked on trials in health and educational research. CAROLE J. TORGERSON is a Senior Research Fellow in the Institute for Effective Education at the University of York, UK. She has published extensively in the field of systematic reviews of randomised trials. She is Co-Chair of the Campbell Collaboration Education Co-ordinating Group. She has also worked on a number of randomised trials in the field of education.

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Table of Contents

• Acknowledgements
• Glossary of Terms
• Background to Controlled Trials
• The Limitations of Before and After Designs
• History of Controlled Trials
• What Is Special about Randomisation?
• Sources of Bias in Randomised Trials
• Placebo and Sham Trials
• Pragmatic and Explanatory Trials
• Designs to Deal with Participants' Preferences
• Cluster Randomised Controlled Trials
• Unequal Randomisation
• Factorial Randomised Controlled Trials
• Pilot Randomised Controlled Trials
• Sample Size and Analytical Issues
• Measuring Outcomes Recruitment into Randomised Trials
• Systematic Reviews of Randomised Controlled Trials
• Economic Evaluation Alongside Randomised Trials
• Conclusions
• References
• Index

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