Development of Sensory Organs

by Guy Richardson (Editor), Doris Wu Ph.D (Editor)

Overview

Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Product Details

ISBN-13:	9780323913720
Publisher:	Elsevier Science
Publication date:	09/26/2025
Series:	Current Topics in Developmental Biology , #165
Pages:	362
Product dimensions:	6.00(w) x 9.00(h) x 0.00(d)

About the Author

Guy Richardson obtained BSc in Neurobiology (Hons) at the University of Sussex in 1974, and then did a PhD at the Max Planck Institut fur biophysikalische Chemie in Göttingen where he used the electromotor system of the electric ray, Torpedo marmorata, as a model system for studying the development of cholinergic motorneurorones and their synapses. He received his DPhil in 1980 and, after four years of postdoctoral research in Germany, returned to Sussex in 1984 to work on the inner ear, a sensory system that has remained the focus of his studies ever since. His work at Sussex has included the development of a cochlear culture system for studying, together with Professors Corne Kros and Ian Russell, the mechanisms of mechano-electrical transduction in mammalian sensory hair cells, the discovery of novel extracellular matrix molecules and cell surface proteins associated with the tectorial membrane and sensory hair bundles of the inner ear, the generation transgenic mouse models for elucidating the basis of various forms of human hereditary deafness, and studies on the mechanisms of antibiotic-induced ototoxicity. Guy was recipient of the Grand Prix Scientifique NRJ from the Institut de France in 2005. He was elected to the Royal Society in 2009 and to the Academy of Medical Science in 2013.

Dr. Wu received her bachelor’s degree from the University of Wisconsin at Stevens Point, her master’s degree from the Department of Physiology at the University of Southern California, and her Ph.D. from the Department of Anatomy (currently the Department of Neurobiology) at the University of California at Los Angeles (UCLA). She received her postdoctoral training from the Mental Retardation Center (now the Intellectual and Developmental Disabilities Research Center) at UCLA and the Department of Genetics at Harvard Medical School. She joined the NIDCD in 1993 and has published many papers on the molecular mechanisms underlying inner ear development.

Table of Contents

Hearing and Balance
1. Control of inner sensory cell differentiation by extracellular signals and transcriptional regulators
Andy Groves
2. Lifelong dynamic maintenance of stereocilia bundles in mammalian auditory hair cells
Gregory Frolenkov
3. The development of polarised hair bundles and their orientation in the sensory organs of the inner ear
Basile Tarchini and Katie Kindt
4. Development of the semicircular canal system of the vertebrate inner ear
Tanya Whitfield
5. Mechanisms and function of calcium signalling in the developing mammalian cochlea
Walter Marcotti and Corne Kros
6. Development of Vestibular Hair Cells and Synapses
Ruth Anne Eatock
7. chapter title yet to decide
Jennifer Stone, Brandon C. Cox and Bradley Walters

Taste
8. A taste for development and regeneration
Linda Barlow and Tom Finger

Vision
9. Genetic and epigenetic control of photoreceptor development
Anand Swaroop
10. Retinal neurogenesis and the diversity of cell fates
Thomas A. Reh
11. Function of the cytoskeleton in mediating the renewal of the photoreceptor outer segment disk membranes
David Williams

Olfactory Neurons
12. Determination of olfactory receptor choice by olfactory neurons
Stavros Lomvardas
13. Development and regeneration of olfactory receptors
James Schwob

Touch Receptors
14. Merkel Cells in Development and Regeneration
Elena Ezhkova
15. Development of mammalian cutaneous sensory corpuscles
JOSE ANTONIO VEGA

What People are Saying About This

From the Publisher

Edited by one of the best scientists in the field, this series presents the latest updates in the field