Development of the Sarcoplasmic Reticulum [NOOK Book]

Overview

Sarcoplasmic reticulum is a form of endoplasmic reticulum found in large quantities in mature muscle cells. Anthony Martonosi presents general information about the development and function of the sarcoplasmic reticulum within a framework of contemporary research on the molecular biology of biosynthetic and signaling processes. Focusing on the development of the sarcoplasmic reticulum, Martonosi demonstrates the regulatory functions that control the production of its molecular components and investigates the ...
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Development of the Sarcoplasmic Reticulum

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Overview

Sarcoplasmic reticulum is a form of endoplasmic reticulum found in large quantities in mature muscle cells. Anthony Martonosi presents general information about the development and function of the sarcoplasmic reticulum within a framework of contemporary research on the molecular biology of biosynthetic and signaling processes. Focusing on the development of the sarcoplasmic reticulum, Martonosi demonstrates the regulatory functions that control the production of its molecular components and investigates the interaction of these lipid and protein molecules with the myogenic, neurogenic and hormonal stimuli present in developing muscle cells. Martonosi provides extensive experimental support throughout the book.

The book contains predominantly black-and-white illustrations, with some color illustrations.

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Editorial Reviews

John Gergely
There is a wealth of information in this book touching on problems of the development of the sarcoplasmic reticulum and of other elements relevant to excitation contraction coupling.
From The Critics
Reviewer:Eugene A Davidson, PhD(Georgetown University School of Medicine)
Description:This book has two separate sections. The first is an 18-chapter compilation of work on muscle development and the second is a nearly 200-page bibliography. As a reference, the latter is strong motivation for investigators to acquire this book.
Purpose:The purpose is to serve as a review of information on the sarcoplasmic reticulum.
Audience:Investigators and fellows are the intended audience.
Features:The initial chapter serves as an overview of muscle development and is followed by discussions of protein expression and degradation, and the role of phospholipids. Formation of the excitation-contraction apparatus is reviewed followed by chapters on channels. Calcium and its role in muscle development and function is discussed from a variety of aspects including regulation of synthesis of several proteins, signal transduction and the acetylcholine receptor.
Assessment:Each of the topics is covered in detail, often with critical analysis of published data. In that regard, this book makes a valuable contribution. A minor caveat is that because of the exhaustive bibliography, the text is constantly interrupted by literature citations. This makes reading somewhat disconnected, but the value of the bibliography far outweighs this inconvenience. This book is highly recommended for all investigators working with muscle.

3 Stars from Doody
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Product Details

  • ISBN-13: 9780203305010
  • Publisher: Taylor & Francis, Inc.
  • Publication date: 8/7/2000
  • Sold by: Barnes & Noble
  • Format: eBook
  • Pages: 632
  • Sales rank: 605,094
  • File size: 9 MB

Table of Contents

Introduction to Muscle Development
Transcriptional Regulation of Gene Expression
The Development of Sarcoplasmic Reticulum in Skeletal Muscle (SR) and the Expression of Ca-AT Pase
The Synthesis and Insertion of Lumenal Sarcoplasmic Reticulum Proteins During Development of Skeletal Muscle
Regulation of Sarcoplasmic Reticulum Protein Composition and Turnover by Proteolysis
Regulation of the Phospholipid Composition of Sarcoplasmic Reticulum During Development
Development of Excitation-Contraction Coupling Apparatus
The Expression of Dihydropyridine Receptor Channel During Skeletal Muscle Development
The Ryanodine Receptor Ca Channel (RyR)
The Role of Ca in the Regulation of the Expression of Ca-AtPase in Muscle and Non-Muscle Cells
The Role of Ca in the Expression of the Endoplasmic Reticulum Chaperon Proteins GRP78(BiP) and GRP94
Transcriptional Regulation of c-fos Gene
Regulation of the Expression of Acetylcholine Receptor (AchR0, in Muscle by Electrical Activity
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