Diabetes and Cardiovascular Disease / Edition 2

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This extensively updated and expanded second edition reflects new research, advances in clinical care, and the growing recognition that diabetes mellitus is a risk factor for cardiovascular disease. Written for the practicing clinician as a comprehensive review of diabetic vascular disease, the book both explains the basic pathophysiology of the disease and details the latest diagnostic and therapeutic approaches. The authors have added new chapters on percutaneous interventional therapy in cardiac and peripheral vascular disease, cardiovascular surgery in diabetes, therapeutic interventions to improve endothelial function in diabetes, PARP activation and nitrosative stress in the development of the cardiovascular system, and PPARs and their emerging role in vascular biology, inflammation, and atherosclerosis.

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Editorial Reviews

Doody's Review Service
Reviewer: Chandra S. Bomma, M.D.(Ochsner Clinic Foundation)
Description: The second edition of this book addresses both the basic science concepts and clinical aspects of diabetes mellitus and its impact on cardiovascular disease. The first half updates the reader's understanding of the pathophysiological mechanisms by which diabetes mellitus impacts the cardiovascular system. The second part covers clinical updates related to diabetes mellitus, including options to avoid end organ damage with an emphasis on cardiovascular disease management. The most recent information gained from clinical trails is presented in conjunction with the current practice guidelines for the management of diabetes and cardiovascular disease.
Purpose: This book brings together the most recent updates about diabetes mellitus and its role in increasing the cardiovascular disease burden.
Audience: This book is appropriate for a wide variety of physicians and physicians-in-training with an interest in cardiovascular disease, including medical students, house officers, cardiologists in training and attending cardiologists.
Features: Topics including diabetes mellitus and heart failure, dyslipidemia and hypertension, coronary artery disease, and peripheral vascular disease have been extensively covered in this book. Basic pathophysiological principles and various clinical trials results and their translation to patient management have been included in this book.
Assessment: This second edition is a timely work by many eminent contributors. It summarizes the vast knowledge about diabetes mellitus and cardiovascular disease into one volume.
Reviews clinical and scientific aspects of diabetic cardiovascular disease, discussing mechanisms and risk factors of diabetes in relation to hypertension, dyslipidemia, thrombosis, atherosclerosis, coronary artery disease, and congestive heart failure. Part I reviews the mechanisms and risk factors for diabetic cardiovascular disease, and Part II focuses on the heart in diabetes mellitus. The peripheral vascular system is the subject of Part III, which addresses epidemiology, mechanisms, methods of assessment, and treatment of this macrovascular disease. Part IV reviews microvascular effects in patients with diabetes mellitus, including retinopathy, nephropathy, neuropathy, and microcirculation of the diabetic foot. Of interest to cardiologists, internists, vascular specialists, diabetologists, endocrinologists, and family physicians. The editors are affiliated with Beth Israel Deaconess Medical Center, Harvard Medical School. Annotation c. Book News, Inc., Portland, OR (booknews.com)

3 Stars from Doody
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Product Details

  • ISBN-13: 9781588294135
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 5/28/2005
  • Series: Contemporary Cardiology Series
  • Edition description: 2nd ed. 2005
  • Edition number: 2
  • Pages: 672
  • Product dimensions: 7.12 (w) x 10.26 (h) x 1.48 (d)

Table of Contents

Part I. Pathophysiology

Effects of Insulin on the Vascular System

Helmut O. Steinberg

Effects of Diabetes and Insulin Resistance on Endothelial Functions

Zhiheng He, Keiko Naruse, and George L. King

Diabetes and Advanced Glycoxidation End-Products

Melpomeni Peppa, Jaime Uribarri, and Helen Vlassara

The Renin-Angiotensin System in Diabetic Cardiovascular Complications

Edward P. Feener

PPARs and Their Emerging Role in Vascular Biology, Inflammation, and Atherosclerosis

Jorge Plutzky

Diabetes and Thrombosis

David J. Schneider and Burton E. Sobel

Role of Estrogens in Vascular Disease in Diabetes: Lessons Learned From the Polycystic Ovary Syndrome

Agathocles Tsatsoulis and Panayiotis Economides

Poly(ADP-Ribose) Polymerase Activation and Nitrosative Stress in the Development of Cardiovascular Disease in Diabetes

Pál Pacher and Csaba Szabó

Adiponectin and the Cardiovascular System

Suketu Shah, Alina Gavrila, and Christos S. Mantzoros

Nitric Oxide and Its Role in Diabetes Mellitus

Michael T. Johnstone and Eli Gelfand

Diabetes and Atherosclerosis

Maria F. Lopes-Virella and Gabriel Virella

The Use of Animal Models to Study Diabetes and Atherosclerosis and Potential Anti-Atherosclerotic Therapies

Peter D. Reaven and Wulf Palinski

Part II. Clinical

A. Risk Factors

The Metabolic Syndrome and Vascular Disease

S. J. Creely, Aresh J. Anwar, and Sudhesh Kumar

Diabetes and Hypertension

Samy I. McFarlane, Amal F. Farag, David Gardner, and James R. Sowers

Diabetes and Dyslipidemia

Asha Thomas-Geevarghese, Catherine Tuck, and Henry N. Ginsberg

B. Microcirculation

Diabetic Retinopathy

Lloyd Paul Aiello and Jerry Cavallerano

Diabetic Nephropathy

Richard J. Solomon and Bijan Roshan

Diabetic Neuropathy

Rayaz A. Malik and Aristidis Veves

Microcirculation of the Diabetic Foot

Chantel Hile and Aristidis Veves

C. Cardiovascular System: Peripheral Vascular System

Epidemiology of Peripheral Vascular Disease

Stephanie G. Wheeler, Nicholas L. Smith, and Edward J. Boyko

Noninvasive Methods to Assess Vascular Function and Pathophysiology

Peter G. Danias and Rola Saouaf

Peripheral Vascular Disease in Patients With Diabetes Mellitus

Bernadette Aulivola, Allen D. Hamdan, and Frank W. LoGerfo

Therapeutic Interventions to Improve Endothelial Function in Diabetes

Lalita Khaodhiar and Aristidis Veves

D. Cardiovascular System: Cardiac

Preoperative Assessment and Perioperative Management of the Surgical Patient With Diabetes Mellitus

Alanna Coolong and Mylan C. Cohen

Diabetes and Percutaneous Interventional Therapy

David P. Lorenz, Joseph P. Carrozza, and Lawrence Garcia

Cardiac Surgery and Diabetes Mellitus

Tanveer A. Khan, Pierre Voisine, and Frank W. Sellke

Heart Failure and Cardiac Dysfunction in Diabetes

Lawrence H. Young, Raymond R. Russell, III, and Deborah Chyun

Diabetes Mellitus and Heart Disease

Michael T. Johnstone and George P. Kinzfogl


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