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From The CriticsReviewer: Sahil Bakshi, D.O. (Ochsner Clinic Foundation)
Description: This book is intended to educate the reader about how diabetes causes and worsens cardiovascular disease and ultimately will be the cause of death in millions of people worldwide.
Purpose: Its purpose is to impart the complex pathophysiology of this disease process, and at the same time be clinically useful.
Audience: Intended to educate physicians and scientists, the book does an excellent job explaining the multifactorial way that diabetes affects the cardiovascular system, such as the metabolic derangements it causes and mechanisms of insulin resistance. The recently discovered deleterious impact on fibrinolysis, platelet function, and coagulation pathways that eventually lead to peripheral and coronary thrombosis are well detailed. Illustrations and tables throughout each chapter simplify such complex pathways and topics.
Features: The book is organized into two main sections. The first explains vascular biology at a molecular level, detailing the various biochemical functions of the endothelium and provides a better understanding of the dysfunction caused by diabetes. The second section concentrates on clinical topics such as the epidemiology, economic burden, and treatment of cardiovascular disease in diabetics. Each chapter is written by physicians and scientists who are specialists in this field from all over the world, including the United States, Europe, and China. A large amount of literature is referenced and the data is evidence-based.
Assessment: Cardiovascular disease is the cause of death for approximately 80,000 diabetic patients each year. Within the last decade, the recognition and awareness of this global pandemic has led to an explosion of basic sciences research and clinical trials. This book does a superb job of summarizing this plethora of information in a reliable manner, making it an excellent reference source.