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Doody's Review ServiceReviewer: Lorraine R. Baer, Pharm.D.(Baer Communications, Ltd)
Description: This book, one in the Medical Management series, provides a comprehensive review of diabetes and cardiovascular disease, with a focus on the pathophysiological role of insulin resistance. The book also provides clinically relevant supportive evidence, making it a valuable tool in therapeutic decision making.
Purpose: The purpose is to provide a comprehensive understanding of the intimate relationship between diabetes and cardiovascular disease, with special emphasis on the pathopysiological links between these two complex conditions. The book also aims to provide clinical evidence for the prevention and treatment of the cardiac manifestations of insulin resistance. These objectives have important clinical significance and the authors provide an up-to-date review of the material.
Audience: The book is suitable for general medical practitioners as well as trainees and specialists in the fields of endocrinology and cardiology. Medical students would find it a beneficial reference as well.
Features: This is a current and comprehensive review of the complex relationship and pathophysiological links between diabetes and cardiovascular disease. There is clinically important emphasis on insulin resistance and its role in prediabetes, fibrinolysis, hyperlipidemia, hypertension, atherosclerosis, as well as polycystic ovary syndrome. The practical management of diabetic patients with hypertension, coronary artery disease, heart failure, dyslipidemia, as well as those with a need for coronary interventions is discussed. There is some discussion about the use of insulin secretagogues versus insulin sensitizers in patients with diabetes and cardiovascular disease, and how the BARI-2D study may help elucidate whether certain classes of drugs have a more favorable affect on the cardiovascular (or macrovascular) effects of diabetes. As to be expected with multiauthored books, there is some overlap. Overall, the book is excellent. Chapter 4 (Hypertension, Diabetes, and the Heart) is especially well-written and well-referenced. Only about half of the chapter authors reference the material they discuss, while the remainder simply provide a list of suggested readings. Although this does not detract from the credibility of the information, it makes it difficult to find sources for further investigation or use of the material.
Assessment: Considering the worldwide epidemic of diabetes (expected to affect 300 million people in year 2025), this book will be a useful addition to the library of medical professionals caring for patients with diabetes or at risk for diabetes. The physical presentation makes the book easy to read and the tables are informative.