Diagnostic Gynecologic and Obstetric Pathology [NOOK Book]


Drs. Christopher P. Crum, Marisa R. Nucci, and Kenneth R. Lee help you diagnose neoplastic and non-neoplastic lesions of the female reproductive tract with their comprehensive update of Diagnostic Gynecologic and Obstetric Pathology. This 2nd Edition provides all of the latest guidance needed to accurately evaluate pathologic features and morphologic patterns. With 650+ new color images, an appendix with algorithms for the use of biomarkers, key points, diagnostic pearls, and ...

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Diagnostic Gynecologic and Obstetric Pathology

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Drs. Christopher P. Crum, Marisa R. Nucci, and Kenneth R. Lee help you diagnose neoplastic and non-neoplastic lesions of the female reproductive tract with their comprehensive update of Diagnostic Gynecologic and Obstetric Pathology. This 2nd Edition provides all of the latest guidance needed to accurately evaluate pathologic features and morphologic patterns. With 650+ new color images, an appendix with algorithms for the use of biomarkers, key points, diagnostic pearls, and more… this title is a must-have for today’s pathologist.

  • Find distinct diagnostic/differential diagnostic criteria for any potential obstetric/gynecologic specimen encountered in practice.
  • Integrate exfoliative cytology, immunohistochemistry, and molecular/genetic testing together with findings gleaned from the traditional open surgical biopsy.
  • Examine the cytologic features of specimens taken from the uterine cervix and corpus, following the Bethesda classification of these lesions.

View more than 2,250 full-color photographs and photomicrographs, ideal for side-by-side comparison to the specimens seen in the laboratory.

  • Make better decisions regarding complex pregnancy situations with a new chapter devoted to the "Placental Correlates of Unanticipated Fetal Death."
  • Experience easier reference with key points and diagnostic pearls at the end of each chapter, and a new appendix on algorithms for the use of biomarkers.
  • Update your cancer assessment skills with the restructured section on pelvic epithelial malignancies, including a new chapter on "Assessing Pelvic Cancer Risk and Intercepting Early Malignancy."
  • Gain the professional insights of new co-editor Dr. Marissa Nucci, an associate professor in pathology at the Harvard Medical School.
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Editorial Reviews

Doody's Review Service
Reviewer: Marina Mosunjac, M.D.(Emory University School of Medicine)
Description: This up-to-date, practice-oriented book provides a comprehensive review of gynecologic and obstetric pathology.
Purpose: It offers a balance of the most up-to-date pathobiology of the diseases and practical approaches in solving complex diagnostic problems of everyday pathology, combined with clinically relevant information about the treatment, prognosis, and follow-up.
Audience: The book is primarily intended for practicing pathologists both in academic and private practice settings. However, the systematic approach to each disease, which includes the presentation, histopathology, differential diagnosis and treatment, accompanied by numerous high quality gross and microscopic pictures as well as comprehensive tables and diagnostic flow charts, will appeal to surgical pathology residents, gynecology residents and practicing gynecologic physicians.
Features: The book covers pathology of the female genital system, gestational disease, and disorders of the peritoneum. There is also a chapter on diseases of the anus, something rarely found in gynecology textbooks although it is a region that often shares common diseases with the gynecology system, such as HPV-related lesions. The chapter on cervical squamous neoplasia includes an up-to-date and comprehensive review of molecular biology and carcinogenesis of the HPV virus and a cytology overview with the detailed description and clinical management of ASCUS. Especially valuable are practical pointers such as guidelines for a positive margin of cone biopsy, problems with interpretation of cauterized margins or how to resolve discordant cytology and biopsy results. A separate chapter on benign cervical pathology is not included, although thorough descriptions of all the benign conditions that can mimic squamous intraepithelial neoplasia are included in the chapter on cervical intraepithelial neoplasia. The chapter on the lesions of benign endometrial disorders covers practical issues in patterns that are commonly associated with dysfunctional bleeding. Several comprehensive tables include the major pathology changes of benign endometrial disorders. However, if you try to search for the term simple or complex endometrial hyperplasia in the index, you will be led to the chapter on endometrial intraepithelial neoplasia (EIN), a term not all gynecologic clinicians or pathologists have adopted yet. Besides wonderful histologic descriptions, differential diagnosis, and immunohistochemical staining patterns of ovarian tumors, a special chapter on intraoperative evaluation of ovarian tumors makes this part of the book a highlight. Many have been waiting for a chapter like this since their residency days in the frozen section room when all of the "yellow tumors" in the ovaries looked the same grossly. This chapter offers another look at ovarian neoplasms from a different perspective grouping them by their gross appearance, clinical presentation and similarities in the cell appearance or structure. This is a wonderful chapter to peek at just before you're going to work on a frozen section of an ovarian mass. The three chapters on gestational disease are packed with excellent gross and microscopic pictures and include more than a few comprehensive tables full of valuable clinical morphological and laboratory data important for differential diagnosis. An additional chapter on gestational disease and the placenta integrates the most common clinical scenarios associated with pathological examination of the placenta offering us a different angle to the same pathological changes described in a previous chapter. Three appendixes are no less important than the rest of the book. The list of common diagnostic terms and comments as well as sample reports should serve as the guidelines for a proper, comprehensive, and complete surgical report, as a means of effective communication of data to clinicians, particularly where much of the information can be lost in unnecessary and long microscopic descriptions.
Assessment: This excellent resource for practicing pathologists, pathology residents, and gynecologic practitioners offers an up-to-date comprehensive review of pathobiology, morphology, new diagnostic techniques, treatment options, and prognosis. At the same time it gives numerous "pearls of wisdom" pointing out practical issues in everyday sign-out. The book is written in a systematic, organized, logical, and easy to read fashion and is accompanied by an abundance of high quality color pictures, comprehensive tables, and diagnostic flow charts.
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Product Details

  • ISBN-13: 9781455708956
  • Publisher: Elsevier Health Sciences
  • Publication date: 2/16/2011
  • Sold by: Barnes & Noble
  • Format: eBook
  • Edition number: 2
  • Pages: 1216
  • File size: 113 MB
  • Note: This product may take a few minutes to download.

Table of Contents

1. Female Genital Tract Development and Disorders of Childhood

2. Noninfectious Inflammatory Disorders of the Vulva

3. Localized Vulvodynia

4. Infectious Disorders of the Lower Genital Tract

5. Benign Cysts, Rests, and Adnexal Tumors of the Vulva

6. Squamous Neoplasia of the Vulva

7. Glandular and Other Malignancies of the Vulva

8. Melanocytic Lesions of the Vulva

9. Soft Tissue Lesions of the Vulva and Vagina

10. Diseases of the Anus

11. Benign Conditions of the Vagina

12. Epithelial and Mixed Epithelial-Stromal Neoplasms of the Vagina

13. Cervical Squamous Neoplasia

14. Glandular Neoplasia of the Cervix

15. Neuroendocrine Carcinoma, Mixed Epithelial/Mesenchymal and Mesenchymal Tumors, and Miscellaneous Lesions of the Cervix

16. Evaluation of the Cyclic Endometrium and Benign Endometrial Disorders

17. Preinvasive Endometrial Neoplasia

18. Altered Endometrial Differentiation Metaplasia

19. Adenocarcinoma, Carcinosarcoma, and Other Epithelial Tumors of the Endometrium

20. Ulterine Mesenchymal Tumors

21. The Fallopian Tube and Borad Ligament

22. Benign Conditions of the Ovary

23. Disorders of the Peritoneum

24. Pathogenesis of Ovarian Cancer

25. Assessing Pelvic Cancer Risk and intercepting Early Malignancy

26. Intraoperative Evaluation of Ovarian Tumors

27. The Pathology of Pelvic-Ovarian Epithelial Epithelial-Stromal Tumors

28. Pathology-Based Management and Outcome of Epithelial Tumors of the Ovary

29. Germ Cell Tumors of the Ovary

30. Sex Cord-Stromal and Miscellaneous Tumors of the Ovary

31. Metastatic Tumors of the Ovary

32. Complications of Previable Pregnancy

33. Trophoblastic Neoplasia

34. Evaluation of the Placenta

35. Placental Correlates of Unanticipated Fetal Death

36. Gestational Diseases and the Placenta

Appendix I: Tumor, Nodes, Metastases TNM, and FIGO Staging of Reproductive Tract Tumors

Appendix II: Common Diagnostic Terms in Use in the Division of Women's and Perinatal Pathology, Brigham and Women's Hospital

Appendix III: Diagnostic Variables Commonly Reported in Resected Genital Tract Neoplasms

Appendix IV: Sample Reports from Brigham and Women's Hospital

Appendix V: Commonly Used ICD-9 Codes

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