Diagnostic Hematology: A Pattern Approach
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Diagnostic Hematology: A Pattern Approach

by Doyen Nguyen, Lawrence Diamond
     
 

Diagnostic hematology is a problem-solving process involving the gathering and analysis of the relevant findings in each case. Based on the combination of clinical and laboratory data, an experienced diagnostician can formulate the overall 'pattern' of a case. The 'pattern approach' to differential diagnosis is an integral component of the diagnostic reasoning of many…  See more details below

Overview

Diagnostic hematology is a problem-solving process involving the gathering and analysis of the relevant findings in each case. Based on the combination of clinical and laboratory data, an experienced diagnostician can formulate the overall 'pattern' of a case. The 'pattern approach' to differential diagnosis is an integral component of the diagnostic reasoning of many expert hematologists.

In this unique textbook the authors present a logical and systematic approach to diagnosis, based on the patterns derived from peripheral blood analysis, flow cytometry immunophenotyping studies and bone marrow examination. Unlike standard textbooks which are organized by specific diseases and thereby assume the reader has reached a diagnosis, this text presents the diagnostic problem as it is investigated in practice.

The patterns formed by different blood and bone marrow disorders are described in detail and illustrated with color photomicrographs, or flow cytometry graphics. The reader is taken through the process of reaching the differential diagnosis. Advice is given on the proper approach to diagnostic work-up and how to avoid common diagnostic pitfalls. The companion CD-ROM, with full instructions given in the appendix, offers the reader the chance to assess real test results, and see the patterns which lead to the final interpretation in over 200 cases.

As a result the reader will develop the skill of pattern recognition and be able to incorporate this diagnostic approach in practice. This is an essential text for physicians practicing hematology and hematopathology, especially those interpreting peripheral blood, flow cytometry and bone marrow specimens; also for technologists and laboratory staff responsible for the screening of full blood counts, the initial review of blood/bone marrow films or immunophenotyping data.

System requirements: Windows 95, Windows 98 or Windows NT. Screen resolution of 800 x 600 with 16 million colours (24-bit). Minimum display: at least 65,000 colours (16-bit).

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Editorial Reviews

Doody's Review Service
Reviewer: LoAnn Peterson, MD (Northwestern University Hospital)
Description: In this practical textbook benign and malignant hematologic disorders that involve blood and bone marrow are covered.
Purpose: The purpose is to emphasize a "pattern approach" to diagnosis that includes both morphologic and immunophenotypic features.
Audience: It is designed for physicians, technologists, and other professionals who interpret blood films, bone marrow biopsies, and flow cytometry immunophenotyping data.
Features: This book is divided into three sections: peripheral blood, flow cytometry, and bone marrow. Several different patterns or constellations of findings are discussed under each section. For example, normocellular bone marrow, hypocellular bone marrow, and megakaryocytic hyperplasia are some of the patterns discussed under bone marrow. The text is extensively illustrated with good quality photomicrographs of peripheral blood and bone marrow and histograms showing flow cytometric data. A CD-ROM is also included. Organization according to a "pattern approach" is logical for hematological diagnoses and sets this book apart from most other textbooks of hematology. The authors emphasize an integrated multi-parameter approach to diagnosis, an important part of current hematologic diagnoses. However, separation of the "blood section" from the "bone marrow section" does have some disadvantages for an integrated approach. For example, the discussion of chronic lymphocytic leukemia is separated into at least three different sections: blood, flow cytometry, and bone marrow. Algorithms to guide the reader would have been useful but are not included.
Assessment: This is a practical, basic book that would be most useful to physicians in training, technologists, and other laboratory professionals involved in morphologic or flow cytometric interpretations of blood or bone marrow. This book is not designed to be a comprehensive reference and the number of citations in the suggested reading list is limited. However, it would still serve as a useful, basic guide to a wide range of hematologic disorders.
3 Stars from Doody
LoAnn Peterson
In this practical textbook benign and malignant hematologic disorders that involve blood and bone marrow are covered. The purpose is to emphasize a ""pattern approach"" to diagnosis that includes both morphologic and immunophenotypic features. It is designed for physicians, technologists, and other professionals who interpret blood films, bone marrow biopsies, and flow cytometry immunophenotyping data. This book is divided into three sections: peripheral blood, flow cytometry, and bone marrow. Several different patterns or constellations of findings are discussed under each section. For example, normocellular bone marrow, hypocellular bone marrow, and megakaryocytic hyperplasia are some of the patterns discussed under bone marrow. The text is extensively illustrated with good quality photomicrographs of peripheral blood and bone marrow and histograms showing flow cytometric data. A CD-ROM is also included. Organization according to a ""pattern approach"" is logical for hematological diagnoses and sets this book apart from most other textbooks of hematology. The authors emphasize an integrated multi-parameter approach to diagnosis, an important part of current hematologic diagnoses. However, separation of the ""blood section"" from the ""bone marrow section"" does have some disadvantages for an integrated approach. For example, the discussion of chronic lymphocytic leukemia is separated into at least three different sections: blood, flow cytometry, and bone marrow. Algorithms to guide the reader would have been useful but are not included. This is a practical, basic book that would be most useful to physicians in training, technologists, and other laboratory professionals involved inmorphologic or flow cytometric interpretations of blood or bone marrow. This book is not designed to be a comprehensive reference and the number of citations in the suggested reading list is limited. However, it would still serve as a useful, basic guide to a wide range of hematologic disorders.
Booknews
Hematologists from St. Bartholomew's Hospital in London introduce an approach to differential diagnosis in their discipline that combines clinical and laboratory data to construct an overall pattern of a case. They explain how to derive patterns from peripheral blood analysis, flow cytometry immunophenotyping studies, and bone marrow examination and to use those to choose which of several possible conditions to begin treating. They include color photomicrographs as an atlas of common and more unusual cases. The accompanying disc contains data and final diagnoses for the more than 200 real cases cited in the text. The approach should be of use to hematologists and hematopathologists, especially those interpreting the three measures, and for technologists and laboratory staff screening full blood counts. Distributed by Oxford U. Press. Annotation c. Book News, Inc., Portland, OR (booknews.com)

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Product Details

ISBN-13:
9780750642477
Publisher:
Taylor & Francis
Publication date:
04/01/2000
Series:
An Arnold Publication Series
Edition description:
BK&CD-ROM
Pages:
480
Product dimensions:
7.72(w) x 10.02(h) x 1.21(d)

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