Diagnostic Issues in Depression and Generalized Anxiety Disorder: Refining the Research Agenda for DSM-V

Diagnostic Issues in Depression and Generalized Anxiety Disorder: Refining the Research Agenda for DSM-V

by David Goldberg, Kenneth S. Kendler, Paul J. Sirovatka, Darrel A. Regier
     
 

ISBN-10: 089042456X

ISBN-13: 9780890424568

Pub. Date: 02/22/2010

Publisher: American Psychiatric Publishing, Incorporated

Generalized anxiety disorder (GAD) and major depression (MD) form the largest group of common mental disorders. These two conditions often occur together, and emerging evidence suggests several similarities between them. As we move toward revising the Diagnostic and Statistical Manual of Mental Disorders for DSM-V, Diagnostic Issues in Depression and Generalized

Overview

Generalized anxiety disorder (GAD) and major depression (MD) form the largest group of common mental disorders. These two conditions often occur together, and emerging evidence suggests several similarities between them. As we move toward revising the Diagnostic and Statistical Manual of Mental Disorders for DSM-V, Diagnostic Issues in Depression and Generalized Anxiety Disorder: Refining the Research Agenda for DSM-V explores the nosologic relationship between GAD and MD.

This book acts as a guidepost for the entire DSM process. It reviews recent scientific advances in our understanding of the interrelationship between GAD and MD, summarizes the body of evidence into a few broad conclusions, and reflects on the implications of these findings for future nosologic efforts. The contributing authors review conceptual issues and empirical data from a variety of perspectives, including genetics, biology, treatment, development, course, predictors, disability, and psychosocial stressors.

Diagnostics Issues in Depression and Generalized Anxiety Disorder develops operationalized criteria for nosologic decisions that enable clinicians to bridge the gap between data and diagnostic recommendations. Not only does the methodology of investigating an active interchange between empirical and conceptual perspectives shed new light on the relationship between GAD and MD, but it also carries implications for the rest of DSM-V.

Product Details

ISBN-13:
9780890424568
Publisher:
American Psychiatric Publishing, Incorporated
Publication date:
02/22/2010
Pages:
400
Product dimensions:
5.90(w) x 8.90(h) x 1.00(d)
Age Range:
18 Years

Table of Contents

Contributors ix

Preface Darrel A. Regier xvii

1 The Problem: Charge to the Conference Kenneth S. Kendler 1

2 The Nosologic Relationship between Generalized Anxiety Disorder and Major Depression John M. Hettema 15

Commentary on “The Nosologic Relationship Between Generalized Anxiety Disorder and Major Depression” Jules Angst Alex Gamma Vladeta Ajdacic Wulf Rössler 41

3 The Biology of Generalized Anxiety Disorder and Major Depressive Disorder: Commonalities and Distinguishing Features Elizabeth I. Martin Charles B. Nemeroff 45

4 What (No) Differences in Responses to Three Classes of Psychotropics Can Teach us About Distinctions Between Generalized Anxiety Disorder and Major Depressive Disorder Toshi A. Furukawa Norio Watanabe Ichiro M. Omori 71

Commentary On “The Biology of Gad and MDD” and “What (No) Differences in Responses to Three Classes of Psychotropics Can Teach Us About Distinctions Between Gad and MDD” David J. Kupfer Ellen Frank 105

5 Psychometric Aspects of Anxiety and Depression David Goldberg 109

Commentary On “Psychometric Aspects of Anxiety and Depression” Patrick E. Shrout 125

6 The Boundary Between Generalized Anxiety Disorder and the Unipolar Mood Disorders: Diagnostic and Psychometric Findings in Clinical Samples Timothy A. Brown 131

7 Major Depression and Generalized Anxiety Disorder in the National Comorbidity Survey Follow-Up Survey Ronald C. Kessler Michael Gruber John M. Hettema Irving Hwang Nancy Sampson Kimberly A. Yonkers 139

8 The Relationship of Generalized Anxiety Disorder and Major Depression Over Time Valery N. Krasnov 171

9 Generalized Anxiety Disorder and Major Depression: Common and Reciprocal Causes D.M. Fergusson L. J. Horwood 179

10 Confirmatory Factor Analysis of Common Mental Disorders Across Cultures K.S. Jacob Martin Prince David Goldberg 191

Commentary On “Confirmatory Factor Analysis of Common Mental Disorders Across Cultures” Dan J. Stein Vikram Patel Gerhard Heinze 211

11 Generalized Anxiety Disorder and Depression: Childhood Risk Factors in a Birth Cohort Followed to Age 32 Years Terrie E. Moffitt Avshalom Caspi HonaLee Harrington Barry Milne Maria Melchior David Goldberg Richie Poulton 217

12 Are There Early Adverse Exposures that Differentiate Depression and Anxiety Risk? Marcus Richards David Goldberg 241

13 Episodes and Disorders of General Anxiety and Depression Ian M. Goodyer 257

14 Are Major Depression and Generalized Anxiety Disorder the Same or Different Disorders? Discussion of the Dunedin and Medical Research Council Birth Cohort Studies and the Three-Generation High Risk Study Myrna M. Weissman Virginia Warner Priya Wickramaratne 271

15 Toward a Primary-Care Friendly DSM-V Classification of Emotional Disorders: An Integrative Approach J. Ormel M. J. Manley 285

16 Psychosocial Origins of Depressive and Anxiety Disorders George W. Brown 303

Commentary On “Psychosocial Origins of Depressive and Anxiety Disorders,” Part 1 Sidney Zisook 333

Commentary On “Psychosocial Origins of Depressive and Anxiety Disorders,” Part 2 Donna E. Stewart 347

17 The Relationship between Generalized Anxiety Disorder and Major Depressive Episode David Goldberg 355

Index 363

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