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Dialysis Amyloid / Edition 1
     

Dialysis Amyloid / Edition 1

by Charles van Ypersele, Tilman B. Drueke
 

ISBN-10: 0192624946

ISBN-13: 9780192624949

Pub. Date: 05/28/1996

Publisher: Oxford University Press, USA

Dialysis amyloidosis is a syndrome observed in dialysis patients characterized initially by joint pain, followed later by joint destruction. At present, development of this syndrome is one of the few complications in these patients. The factors involved in the genesis of this syndrome are not yet known with certainty and there is as yet no proven efficacious

Overview

Dialysis amyloidosis is a syndrome observed in dialysis patients characterized initially by joint pain, followed later by joint destruction. At present, development of this syndrome is one of the few complications in these patients. The factors involved in the genesis of this syndrome are not yet known with certainty and there is as yet no proven efficacious treatment other than renal transplantation. As a result, the interest in this topic among nephrologists remains very high.
This book respond to this interest by providing general information on the pathophysiology and clinical aspects of all types of amyloidosis. The recently discovered B2 type of dialysis amyloidosis, a serious complication which affects patients suffering from chronic renal failure,is fully covered from the clinical and pathological features to the physiological and pathophysiological aspects. This book will give nephrologists and rheumatologists a clear understanding of the dialysis amyloidosis syndrome as well as making a valuable contribution to identifying strategies for treatment and prevention.

Product Details

ISBN-13:
9780192624949
Publisher:
Oxford University Press, USA
Publication date:
05/28/1996
Series:
Oxford Clinical Nephrology Series
Edition description:
New Edition
Pages:
296
Product dimensions:
6.81(w) x 9.75(h) x 0.88(d)

Table of Contents

Part I: General aspects of amyloidosios
1. Pathpophysiology of amyloidogenesis
2. Various clinical types of amyloidosis
Part II: Clinical characteristics of *B2=microglobulin amyloidosis
3. Arthropathy and carpal tunnel syndrome of *B2-microglobulin amyloidosis
4. Radiology of dialysis amyloidosis
5. Ultrasonography of the joints
6. Whole-body scintigraphy
Part III: Pathology of *B2-microglobulin deposits
7. Composition of *B2-microglobulin deposits
8. Description, localization, and progression of B2-microglobulin dialysis-related amyloid deposition
Part IV: Physiopathology of *B2-microglobulin accumulation and deposition
9. Characteristics of *B2-microglobulin metabolism
10. Involvement of *B2- microglobulin modified with AGEs in dialysis-related amyloidosis
11. Factors modifying removal and production of *B2-microglobulin
12. Determinants of fibril precipitation and aggregation in amyloid deposits.
Part IV: Review of the clinical evidence on the prophylactic and therapeutic approaches to *B2-microglobulin amyloidosis
13. Prevention and treatment of *B2-microglobulin amyloidosis

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