Diffusion MRI: From Quantitative Measurement to In vivo Neuroanatomy

Overview

Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments.

Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo.

This book covers the ...

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Diffusion MRI: From Quantitative Measurement to In vivo Neuroanatomy

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Overview

Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments.

Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo.

This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie.

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Editorial Reviews

From the Publisher
"A thorough and exciting review of the diffusion MRI techniques that are going to rewrite our knowledge of the long tract anatomy of the human brain. Extremely well written and illustrated." - Michael S. Gazzaniga, Director, Sage Center for the Study of Mind, University of California, Santa Barbara, USA

"25 years after its debut, diffusion MRI today provides us with beautiful, marvelous images of connecting wires within the human brain, and this is achieved just by placing healthy subjects or patients in the middle of a strong magnet. How is this miracle possible? What could we expect from the knowledge of the brain connectome? This beautifully illustrated book addresses these questions with great clarity. The book is highly recommendable to all those who are interested in the links between brain structure and function." - Denis Le Bihan, Member of the Institut de France, Academy of Sciences; Director, NeuroSpin; CEA-Saclay Center, Gif-sur-Yvette, France

"Unbelievable as it may seem, we know almost nothing about the real connectivity of the human cerebral cortex.What we think we know is mostly inferred from results obtained in the monkey.This book provides an exciting exploration of diffusion tensor imaging, a method that can start to close this gap.The editors, who are themselves pioneers in this field, have assembled authoritative chapters on the promises that lie ahead and the challenges that will be encountered." - Marsel Mesulam, Ruth and Evelyn Dunbar Professor of Neurology, Psychiatry and Psychology; Director, The Cognitive Neurology and Alzheimer's Disease Center (CNADC), Feinberg School of Medicine, Northwestern University, Chicago, USA

"Diffusion MRI has tremendous potential for elucidating brain structure and circuitry in health and disease, but the approach is fraught withmethodological and interpretational challenges. This excellent and authoritative book edited by Johansen-Berg and Behrens is an invaluable resource for everyone using diffusion MRI or wanting to learn more about it." - David C. Van Essen, Edison Professor and Department Head, Anatomy and Neurobiology Department, Washington University School of Medicine, St. Louis, USA

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Product Details

  • ISBN-13: 9780123964601
  • Publisher: Elsevier Science
  • Publication date: 12/10/2013
  • Edition number: 2
  • Pages: 632
  • Sales rank: 1,110,416
  • Product dimensions: 6.10 (w) x 9.10 (h) x 2.00 (d)

Table of Contents

Section I: Introduction to Diffusion MRI 1. Introduction to diffusion MR 2. Pulse Sequences for Diffusion-Weighted MRI 3. Diffusion Acquisition: Pushing the Boundaries 4. Geometric Distortions in Diffusion MRI 5. Gaussian Modeling of the Diffusion Signal 6. Multiple Fibers: Beyond the Diffusion Tensor

Section II: Diffusion MRI for Quantitative Measurement 7. White Matter Structure: A Microscopist's View 8. The Biological Basis of Diffusion Anisotropy 9. Inferring Microstructural Information of White Matter from Diffusion MRI 10. Cross-Subject Comparison of Local Diffusion MRI Parameters 11. Diffusion MRI in Neurological Disorders 12. Diffusion Tensor Imaging in the Study of Aging and Age-Associated Neural Disease 13. Diffusion Imaging in teh Developing Brain 14. Individual Differences in White Matter Microstructure in the Healthy Brain 15. Diffusion Tensor Imaging and its Applications to Schizophrenia and Related Disorders

Section III: Diffusion MRI for In Vivo Neuroanatomy 16. Mapping Connections in Humans and Non-Human Primates: Aspirations and Challenges for Diffusion Imaging 17. Classic and Contemporary Neural Tract-Tracing Techniques 18. The Human Connectome: Linking Structure and Function in the Human Brain 19. MR Diffusion Tractography 20. Validation of Tractography 21. Connectivity Fingerprinting of Gray Matter 22. Contribution of Diffusion Tractography to the Anatomy of Language 23. Presurgical Tractography Applications 24. Comparing Connections in the Brains of Humans and Other Primates Using Diffusion-Weighted Imaging 25. Imaging Structure and Function

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