Discovering Genomics, Proteomics, and Bioinformatics / Edition 1

Discovering Genomics, Proteomics, and Bioinformatics / Edition 1

by A. Malcolm Campbell, Laurie J. Heyer
     
 

ISBN-10: 0805347224

ISBN-13: 9780805347227

Pub. Date: 09/13/2002

Publisher: Benjamin Cummings

Discovering Genomics, Proteomics, and Bioinformatics combines integrated Web exercises with a problem-solving approach to train readers in basic hands-on genomic analysis. The authors present global problems, then provide the tools of genomic analysis to help readers dissect the answer, thus encouraging critical thinking skills. Short boxed readings…  See more details below

Overview

Discovering Genomics, Proteomics, and Bioinformatics combines integrated Web exercises with a problem-solving approach to train readers in basic hands-on genomic analysis. The authors present global problems, then provide the tools of genomic analysis to help readers dissect the answer, thus encouraging critical thinking skills. Short boxed readings called "Math Minutes" explain the math behind the biology. For anyone interested in genomics, proteomics, or bioinformatics.

Product Details

ISBN-13:
9780805347227
Publisher:
Benjamin Cummings
Publication date:
09/13/2002
Edition description:
BK&CD-ROM
Pages:
352
Product dimensions:
8.50(w) x 10.72(h) x 0.59(d)

Table of Contents

Foreword
Preface
Acknowledgments
Unit 1Genome Sequences1
Ch. 1Genome Sequence Acquisition and Analysis2
1.1Defining Genomes3
1.2What Have We Learned from the Human Genome Draft Sequences?17
Ch. 2Genome Sequences Answer Interesting Questions30
2.1Evolution of Genomes31
2.2Genomic Identifications46
2.3Biomedical Genome Research57
Ch. 3Genomic Variations69
3.1Environmental Case Study70
3.2Human Genomic Variation76
3.3The Ultimate Genomic Phenotype-Death?89
3.4Ethical Consequences of Genomic Variations93
Unit 2Genome Expression105
Ch. 4Basic Research with DNA Microarrays106
4.1Introduction to Microarrays107
4.2Alternative Uses of DNA Microarrays128
Ch. 5Applied Research with DNA Microarrays137
5.1Cancer and Genomic Microarrays138
5.2Improving Health Care with DNA Microarrays146
Ch. 6Proteomics161
6.1Introduction162
6.2Protein 3D Structures171
6.3Protein Interaction Networks176
6.4Measuring Proteins183
Unit 3Whole Genome Perspective205
Ch. 7Genomic Circuits in Single Genes206
7.1Dissecting a Gene's Circuitry207
7.2Integrating Single-Gene Circuits229
Ch. 8Integrated Genomic Circuits232
8.1Simple Integrated Circuits233
8.2Complex Integrated Circuits244
Ch. 9Modeling Whole-Genome Circuits265
9.1Is Genomics a New Perspective?266
9.2Can We Model Entire Eukaryotes with a Systems Approach?267
9.3Will Systems Biology Go Systemic?274
Unit 4Transition from Genetics to Genomics: Medical Case Studies277
Ch. 10What's Wrong with My Child?278
10.1First Patients279
10.2The Next Steps in Understanding the Disease284
Ch. 11Why Can't I Just Take a Pill to Lose Weight?306
Ch. 12Why Can't We Cure More Diseases?320
Glossary331
Credits341
Index345

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