Diseases of the Liver and Biliary System in Children

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“An excellent up-to-date comprehensive and practical text book dealing with all aspects of paediatric hepatobiliary disease. It will be useful to both generalists and specialists as it is clinically focused with a problem-solving approach and should be useful for day-to-day as well as more esoteric clinical problems. I found it useful in my general paediatric practice and my trainees have also found it useful. It is very practical with a diagnostic approach and lots of tables and clinical pathways to follow when ...
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Williston, Vermont, U.S.A. 2004 Hardcover New 1405106603. FLAWLESS COPY, BRAND NEW, PRISTINE, NEVER OPENED; 512 pages--An extremely practical text, this new edition of Diseases ... of the Liver and Biliary System in Children covers the essentials of paediatric hepatology. The range of material is wide and has been revised and updated to include the latest advances. Many helpful algorithms and tables are included and the references at the end of each chapter have been carefully selected so as to provide the most up-to-date information available. A concluding section comprising some 100 carefully annotated plates, completes this text. Containing the contributions of 23 internationally acclaimed authorities, active both clinically and in research, the book provides an essential guide to the diagnosis and management of paediatric liver diseases, both common and uncommon for all those involved in the care of the child with liver disease. Diseases of the Liver and Biliary System in Children has become THE REFERENCE Read more Show Less

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Overview

“An excellent up-to-date comprehensive and practical text book dealing with all aspects of paediatric hepatobiliary disease. It will be useful to both generalists and specialists as it is clinically focused with a problem-solving approach and should be useful for day-to-day as well as more esoteric clinical problems. I found it useful in my general paediatric practice and my trainees have also found it useful. It is very practical with a diagnostic approach and lots of tables and clinical pathways to follow when confronted with day-to-day clinical problems. I have road-tested it in real life with good effect.” - Judging Panel, 2004 BMA Medical Book Competition

Diseases of the Liver and Biliary System in Children, Third Edition provides a practical approach to the diagnosis and management of paediatric liver diseases, highlighting the importance of multidisciplinary team working and holistic management of the child and family. This fully revised edition has also been updated to cover recent advances in paediatric hepatology. It includes new chapters describing the effects of liver disease in pregnancy on mother and child through to adolescence. With increasing numbers of young people surviving into adult life this edition addresses the importance of managing adolescent transition effectively.

Trainees, practising paediatric gastroenterologists and hepatologists will welcome the practical approach outlined in this text, while other healthcare professionals involved in the management of liver disease in children will find it an accessible and comprehensive reference.

The book contains predominantly black-and-white illustrations, with some color illustrations.

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Editorial Reviews

Harvey L. Sharp
This book provides an easy to read clinical assessment of this exciting and important field of medicine. The algorithms are good. The purpose is to provide a practical approach to pediatric liver disease, highlighted by development of section categories (i.e., neonatal liver disease, acute liver disease, etc.). There are excellent chapters on surgical management, including liver and liver-bowel transplantation. There is a unique and important chapter on dental care of children with liver disease. This book fulfills a clinical need not previously met for the non-expert. The editor is right on target—this book is for the non-specialist pediatrician and trainee, as well as trainees in pediatric gastroenterology, hepatology, and surgery. Previously trained pediatric gastroenterologists with weak exposure to hepatology will greatly benefit from this text. The contributors predominantly have a British background and all have expertise in the chapters written. The editor covers how to diagnose and treat acute liver disease with an appropriate emphasis on the infant. Hepatitis and inherited disorders are practically covered. Diseases of the biliary tree are very well done. The approach includes assessment of the whole child, including the skin and systemic disorders. The chapter on acute liver failure is excellent. For the most part, the tables, figures, and pictures in the color atlas are meaningful. Some of the photomicrography of liver pathology is too small for interpretive learning, especially by the non-expert. There is a little too much duplication although it is cross referenced well. What this book offers is a very readable clinical approach to pediatric liver diseasenot available in single chapters in adult hepatology texts or in more general pediatric gastroenterology textbooks. Suchy's Liver Disease in Children (Mosby-Year Book, Inc, 1994) provides more in-depth exposure for specialists. This book fills the need for the non-expert and those in training for immediate clinical answers.
Booknews
The editor is affiliated with The Birmingham Childrens Hospital, UK; the 21 contributors are from the UK, except for a few from the US and Canada. Eighteen chapters are arranged in sections on assessment; the neonate; acute disease; older children; metabolic liver disease; management of chronic disease; the liver and other organs; surgical management; and transplantation. Coverage is wide, including such aspects as the psychology of parents of children on transplant waiting lists to the genetic disturbances of bilirubin and bile salt transport in the neonate. Annotation c. Book News, Inc., Portland, OR (booknews.com)
From The Critics
Reviewer: Harvey L. Sharp, MD(University of Minnesota)
Description: This book provides an easy to read clinical assessment of this exciting and important field of medicine. The algorithms are good.
Purpose: The purpose is to provide a practical approach to pediatric liver disease, highlighted by development of section categories (i.e., neonatal liver disease, acute liver disease, etc.). There are excellent chapters on surgical management, including liver and liver-bowel transplantation. There is a unique and important chapter on dental care of children with liver disease. This book fulfills a clinical need not previously met for the non-expert.
Audience: The editor is right on target — this book is for the non-specialist pediatrician and trainee, as well as trainees in pediatric gastroenterology, hepatology, and surgery. Previously trained pediatric gastroenterologists with weak exposure to hepatology will greatly benefit from this text. The contributors predominantly have a British background and all have expertise in the chapters written.
Features: The editor covers how to diagnose and treat acute liver disease with an appropriate emphasis on the infant. Hepatitis and inherited disorders are practically covered. Diseases of the biliary tree are very well done. The approach includes assessment of the whole child, including the skin and systemic disorders. The chapter on acute liver failure is excellent. For the most part, the tables, figures, and pictures in the color atlas are meaningful. Some of the photomicrography of liver pathology is too small for interpretive learning, especially by the non-expert. There is a little too much duplication although it is cross referenced well.
Assessment: What this book offers is a very readable clinical approach to pediatric liver disease not available in single chapters in adult hepatology texts or in more general pediatric gastroenterology textbooks. Suchy's Liver Disease in Children (Mosby-Year Book, Inc, 1994) provides more in-depth exposure for specialists. This book fills the need for the non-expert and those in training for immediate clinical answers.

3 Stars from Doody
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Product Details

  • ISBN-13: 9781405106603
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 1/28/2004
  • Edition description: REV
  • Edition number: 2
  • Pages: 512
  • Product dimensions: 8.86 (w) x 10.94 (h) x 1.18 (d)

Meet the Author

Dr Deirdre Kelly is a consultant pediatric hepatologist at the Liver Unit of Birmingham Children's Hospital and Reader in Paediatric Hepatology at the University of Birmingham.

She was born and brought up in Calcutta, India, in the post-Raj era while her father was working for Lipton's Tea. She spent her early childhood in India and went to boarding school in Dublin when she was 12 years old. She first decided to become a doctor at the age of 8 and despite much opposition from family and nuns at her convent school, persisted and went to Trinity College Dublin to study medicine in 1967.

She originally planned to be a General Practitioner but in her Senior House Officer days was encouraged to take an academic line and apply for General Medicine rotations and take the membership exams. She trained first in adult medicine, and then in gastroenterology and hepatology in Dublin with Professor Donald Weir who encouraged her to do an MD thesis on folate catabolism with Professor John Scott, a world authority on folate metabolism.

While in Dublin she had her two delightful sons while juggling research/academic medicine/clinical practice and discovered the joys of being a mother.

In 1982, she moved to London to work with Dame Sheila Sherlock at the Royal Free Hospital, where she became interested in pediatric hepatology. Dr Kelly retrained in pediatrics with Professor Otto Wolff at Great Ormond Street and Professor John Walker Smith at Queen Elizabeth Hospital, Hackney.

In 1987 she went to work as an Assistant Professor in Pediatric Gastroenterology and Hepatology at the University of Nebraska in Omaha US.

Dr Kelly used this time to learn about caring for children undergoing liver transplantation. Equipped with these new skills she returned to Birmingham in 1989 to set up a National Liver Unit to care for children with liver disease and undergoing liver transplantation.

The Unit has been very successful and is one of the busiest pediatric liver transplant programmes with survival rates of > 90%. Dr Kelly now has three other consultant colleagues and a team of junior doctors, research fellows, specialist nurses and other valuable members of the multidisciplinary team.

They have achieved international standards for care of children with liver disease and liver transplantation and currently are the only unit in the UK to provide small bowel transplantation for children.

They have expanded their research programme to look at mechanisms which control the development of biliary epithelial cells, the underlying mechanisms for the pathophysiology of malnutrition in children with liver disease and the natural history and management of chronic viral hepatitis in childhood. They have a major interest in the outcome and quality of life following transplantation.

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Table of Contents

List of Contributors
Foreword
Preface
Acknowledgements
1 Supporting the Child and Family 1
2 Useful Investigations in the Assessment of Liver Disease 17
3 Interventional Radiology and Invasive Diagnostic Imaging 25
4 The Jaundiced Baby 35
5 The Acutely Ill Baby 74
6 Acute Hepatitis 92
7 Fulminant Hepatitis and Acute Liver Failure 107
8 Chronic Hepatitis 127
9 Congenital and Structural Abnormalities of the Liver 162
10 Non-alcoholic Steatosis 183
11 Hepatobiliary Disease in Cystic Fibrosis 197
12 Metabolic Liver Disease in the Infant and Older Child 211
13 Disorders of Copper Metabolism 243
14 Complications and Management of Chronic Liver Disease 259
15 The Liver in Systemic Illness 282
16 Skin Disorders in Liver Disease 300
17 Dental Care of Children with Liver Disease 313
18 Surgical Disorders of the Liver and Bile Ducts and Portal Hypertension 324
19 Primary Hepatic Tumours 363
20 Liver Transplantation 378
21 Small Bowel Transplantation in Children 402
22 Liver Disease in the Developing World 421
Atlas section 439
Index 475
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