Disorders of Voluntary Muscleby George Karpati
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This major new edition fulfils the need for a single-volume, up-to-date information resource on the etiology, pathogenesis, diagnosis and treatment of diseases of skeletal muscles, including the muscular dystrophies, mitochondrial myopathies, metabolic myopathies, ion channel disorders, and dysimmune myopathies. As background to the clinical coverage, relevant information on advances in molecular and developmental biology, immunopathology, mitochondrial biology, ion-channel dynamics, cell membrane and signal transduction science, and imaging technology is summarized. Combining essential new knowledge with the fundamentals of history-taking and clinical examination, this extensively illustrated book will continue to be the mainstay for practising physicians and biomedical scientists concerned with muscle disease. Regular updates on the clinical and basic science aspects of muscle disease - written mainly by rising stars of myology - will be published on an accompanying website.
Description: This book presents the latest information on the etiology, pathogenesis, and clinical description of skeletal muscle disease. Topics include: mitochondrial myopathies, ion channel disorders, muscular dystrophies, congenital myopathies, dysimmune myopathies, toxic myopathies, and neuromuscular junction diseases. The extensive coverage of the scientific basis and methods of investigation is a welcome component. The previous edition was published in 1994.
Purpose: This book is intended to provide an up-to-date reference for the clinical and basic science aspects of the field. Without question, these are invaluable objectives because there has been a rapid expansion in information since the publication of the previous edition. The authors have provided us an outstanding book.
Audience: I agree with the authors that the book will appeal to a wide range of readers. Practicing clinicians in neurology, rheumatology, pediatrics, orthopedics, and physiatry as well as medical students, graduate students, clinical scientists, and basic scientists all should find its contents very useful. The list of contributors reads like a "Who's Who" in this field.
Features: Both clinical and basic science aspects of muscle disease are covered. There are newly described entities as well as updates on well known diseases. The most remarkable feature of this book is the comprehensive coverage of new information combined with the insights from the best thinkers that could be brought together.
Assessment: Hands down, this book is the best current publication in its category. The seventh edition is well timed to capture the massive increase of information published since the previous edition of 1994.
- Cambridge University Press
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- 46 MB
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Meet the Author
George Karpati is Isaac Walton Killam Chair and Professor at the Department of Neurology and Neurosurgery, McGill University, and the Montreal Neurological Institute, Montreal, Quebec, Canada.
David Hilton-Jones is Clinical Director of the Muscular Dystrophy Campaign Muscle and Nerve Centre, John Radcliffe Hospital, Oxford, UK.
Kate Bushby is Professor of Neuromuscular Genetics at the Institute of Human Genetics, International Centre for Life, Newcastle upon Tyne, UK.
Robert C. Griggs is Professor of Neurology, Medicine, Pediatrics, Pathology and Laboratory Medicine at the Department of Neurology, University of Rochester School of Medicine and Dentistry and Strong Memorial Hospital, Rochester, New York, USA. He is also Chair of the Muscle Study Group Executive Committee.
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