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The processes of DNA recombination and repair are vital to cell integr ity — an error can lead to a disease such as cancer. Filling a need f or timely and accurate information on the subject, this book studies t he cellular processes involved in DNA recombination and repair by high lighting a selection of issues currently at the forefront of understan ding.
The book contains black-and-white illustrations.
|List of contributors|
|1||Molecular processing of DNA folding anomalies in Escherichia coli||1|
|2||Double-strand break repair and VDJ recombination||16|
|4||Mismatch repair and cancer||66|
|5||Enzymology of human nucleotide excision repair||99|
|6||Transcription-coupled and global genome repair in yeast and humans||138|
|7||The ATM gene and stress response||166|
|8||p53 and the integrated response to DNA damage||202|