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Doody's Review ServiceReviewer: Rachel R Chennault, PhD (American College of Clinical Pharmacy)
Description: This is a comprehensive guide through the mechanisms of action of major drugs, including prescription medications, over-the-counter drugs, vitamins, and herbal remedies, as well as their potential for interactions when taken in combination.
Purpose: As an increasing number of adults in the United States describe taking multiple medications simultaneously, the potential for dangerous interactions among concomitant drug therapies also rises. This book addresses this important concern by reviewing the top 300 most prescribed drugs in the United States available to treat more than 80 different diseases or conditions, providing an in-depth description of the drugs' mechanisms of action, discussing side effects and adverse drug events associated with each drug's use, and warnings about a drug's potential interactions with a given medication, therapeutic group, and/or dietary supplement to avoid potentially serious consequences of drug-drug interactions.
Audience: This will serve as an invaluable guide for various medical professionals and basic scientists, as well as pharmacology students with an interest in understanding the relevance of drug interactions to pharmacotherapy. As a widely recognized expert and acclaimed author in the field of pharmacology, Dr. Choe lends authority to this discussion.
Features: The book is organized into eight parts based on body systems (i.e., gastrointestinal, endocrine, neuronal, etc.). Chapters in each of these parts address various disease states relevant to the body system and systematically describe the most commonly prescribed drugs for treating each disease or condition, their mechanisms of action, as well as side effects and the biological basis for interaction with other drugs. The appendixes group these major drugs by therapeutic classification and further describe interactions that are shared among each group's members with other groups or individual drug agents.
Assessment: The book is extremely useful as a quick yet thorough guide through the wealth of information that exists for the most common drug therapies. Although readers may find expanded coverage of much of the same material in other books, such as Clinical Drug Data, 11th edition, Smith et al. (McGraw-Hill, 2010), this one is unique in its careful consideration of the relevance of dietary supplements to the discussion of drug interactions.