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Doody's Review ServiceReviewer: Thomas L. Pazdernik, PhD (University of Kansas Medical Center)
Description: This is a how-to book of cutting-edge technologies in drug delivery systems written by a team of experts in pharmaceutical sciences from academia and industry.
Purpose: The aim is to publish descriptions of selective technologies used in drug delivery systems. Important new technologies, such as nanoparticles, and new therapeutic applications are included. This goal is well developed by these experts.
Audience: This book is written for pharmaceutical scientists working in academia or industry. It contains useful information for pharmaceutical physicians and scientists in many disciplines, including chemical engineering, protein engineering, and gene therapy, who have an interest in drug delivery systems.
Features: A concise overview of drug delivery systems begins the book, followed by chapters dealing with the use of adeno-associated virus capsid in gene transfer, delivering small interfering RNAs for novel therapeutic actions, the use of catheters for the chronic administration of drugs into brain tissues, transdermal drug delivery systems, protein particles that are engineered for pulmonary drug delivery, a new technology to deliver drugs across the blood-brain barrier, the use of liposomal technology for the delivery of anticancer drugs, the use of pH responsive nanoparticles for the delivery of anticancer drugs, and advances in extended-release technologies for oral medications. Each chapter discusses the principles, detailed experimental protocols, and results of drug delivery of the technique.
Assessment: This is a powerful reference that provides concise and systematic description of drug delivery technologies that should be useful for the many companies developing drug delivery technologies as well as academicians who are investigating the principles of drug delivery systems.