Drug Discovery and Development: Technology In Transition

Drug Discovery and Development: Technology In Transition

by Humphrey P. Rang
     
 

ISBN-10: 0443064202

ISBN-13: 9780443064203

Pub. Date: 01/18/2006

Publisher: Elsevier Health Sciences

This title is directed primarily toward health care professionals outside the United States. An ideal introduction to the pharmaceutical industry, this book describes the process of bringing a new drug to the marketplace. It explains why, although thousands of compounds show initial promise, only a small handful will be developed for human clinical trials and

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Overview

This title is directed primarily toward health care professionals outside the United States. An ideal introduction to the pharmaceutical industry, this book describes the process of bringing a new drug to the marketplace. It explains why, although thousands of compounds show initial promise, only a small handful will be developed for human clinical trials and perhaps only one will become an approved drug. Describing the huge complexities involved, it shows how new molecular understanding and techniques can make the process more targeted and successful.

• Includes the new molecular techniques of drug design and development.
• Discusses current therapeutic needs.
• Covers pharmacoepidemiology and pharmacoeconomics.
• Edited by Humphrey Rang, who is also known throughout the world as a co-author of the enormously successful and authoritative textbook, Pharmacology, now in its fifth edition.
• Foreword by Daniel Vasella, CEO, Novartis International.
• Includes contributors from both the pharmaceutical industry and universities.

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Product Details

ISBN-13:
9780443064203
Publisher:
Elsevier Health Sciences
Publication date:
01/18/2006
Edition description:
Older Edition
Pages:
360
Product dimensions:
7.70(w) x 10.40(h) x 0.80(d)

Table of Contents

Section 1: Introduction:

Development of the pharmaceutical industry

Nature of disease and the purpose of therapy
Therapeutic modalities

Section 2: Drug discovery

The drug discovery process:

General principles and some case histories

Choosing the project

Choosing the target

The role of genomics and bioinformatics

High throughput screening

The role of chemistry in the drug discovery process

Pharmacokinetic issues in drug discovery

Pharmacology: its role in drug discovery

Biopharmaceuticals

Patent issues in drug discovery

Organisation of a large drug discovery department

Section 3: Drug development:

Introduction

Assessing drug safety

Pharmaceutical development

Clinical development

Protecting the assets: patenting and intellectual property

Regulatory affairs

Marketing the drug

Section 4: Facts and figures:

Drug discovery and development: Facts and figures

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