Drug Discrimination: Applications to Medicinal Chemistry and Drug Studies

Overview

Although somewhat labor intensive, Drug Discrimination (DD) is of enormous applicability to the understanding of drug action. Drug Discrimination: Applications to Medicinal Chemistry and Drug Studies covers the practical applications of drug discrimination studies for medicinal chemistry, including strengths and limitations versus other pharmacological methods for evaluating drug action. The book provides medicinal chemists with a fuller understanding of the nature and use of drug discrimination studies for ...

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Drug Discrimination: Applications to Medicinal Chemistry and Drug Studies

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Overview

Although somewhat labor intensive, Drug Discrimination (DD) is of enormous applicability to the understanding of drug action. Drug Discrimination: Applications to Medicinal Chemistry and Drug Studies covers the practical applications of drug discrimination studies for medicinal chemistry, including strengths and limitations versus other pharmacological methods for evaluating drug action. The book provides medicinal chemists with a fuller understanding of the nature and use of drug discrimination studies for evaluating the action of drugs while helping pharmacologists understand and better interact with medicinal chemists and drug designers when sharing pharmacologic data.

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Product Details

  • ISBN-13: 9780470433522
  • Publisher: Wiley
  • Publication date: 8/23/2011
  • Edition number: 1
  • Pages: 530
  • Product dimensions: 6.30 (w) x 9.40 (h) x 1.30 (d)

Table of Contents

Part I.

Chapter 1. An Introduction to Drug Discrimination.

Chapter 2. Methodological Considerations.

Chapter 3. Drug Discrimination: Practical Considerations.

Chapter 4. Role of Stereochemistry in Drug Discrimination Studies.

Chapter 5. Drug Discrimination and In Vivo Structure-Activity Relationships.

Chapter 6. Drug Discrimination and Mechanisms of Drug Action.

Chapter 7. Drug Discrimination and Development of Novel Agents and Pharmacological Tools.

Part II.

Chapter 8. Perceptual Drug Discriminative Aspects of the Endocannabinoid Signaling System in Animals and Man (Torbjörn U. C. Järbe).

Chapter 9. Discriminative Stimulus Properties of Receptor Antagonists (Joseph H. Porter).

Chapter 10. The Discrimination of Drug Mixtures (P. Stolerman).

Chapter 11. Making the Right Choice: Lessons From Drug Discrimination for Research on Drug Reinforcement and Drug Self-Administration (S. Stevens Negus and Matthew L. Banks).

Chapter 12. Inhalant Drug Discrimination: Methodology, Literature Review and Future Directions (Keith L. Shelton and Robert L. Balster).

Chapter 13. Drug Discrimination Studies in Rhesus Monkeys: Drug Dependence and Withdrawal (Jun-Xu Li, Lisa R. Gerak, and Charles P. France).

Chapter 14. Human Drug Discrimination: Methodological Considerations and Application to Elucidating the Neurophar,acology of Amphetamines (Craig R. Rush, Andrea R. Vansickel, and William W. Stoops).

Chapter 15. Nicotine Discrimination in Humans (Kenneth A. Perkins).

Chapter 16. Drug Discrimination: A Perspective (Francis C. Colpaert).

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Sort by: Showing all of 2 Customer Reviews
  • Anonymous

    Posted October 8, 2011

    Highly Recommended

    This book was well worth the money spent - I found it very insightful and helpful in my studies.

    1 out of 1 people found this review helpful.

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  • Posted September 12, 2011

    more from this reviewer

    What!

    Don't be dumb enough to buy this because I surely wasn't!This book is over 100 bucks!

    0 out of 1 people found this review helpful.

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