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Doody's Review ServiceReviewer: Steven H. Goldberg, MD (Kaiser Permanente)
Description: This book contains a well-referenced listing of numerous drugs and their cutaneous side effects. It is unique in allowing the reader to look up skin reaction patterns associated with a particular drug or vice versa.
Purpose: It is intended o provide the clinician with the necessary reference for determining which drug may produce any given skin eruption.
Audience: Dermatologists, pharmacologists, and interested clinicians are the audience for this reference.
Features: The book provides an alphabetical listing of more than 500 commonly prescribed drugs. Each drug is presented with its generic name and all known trade names it is marketed under, as well as the category or class it belongs to pharmacologically. Following are cutaneous reaction patterns each listed with references in the known literature arranged chronologically. Included is an excellent section discussing 25 of the most common reaction patterns found in dermatology, many of which are well illustrated in color photographs. The text concludes with an alphabetical listing of 82 reaction patterns and the drugs responsible in producing them.
Assessment: The alphabetical listings of drugs and reaction patterns allows the reader to rapidly find the necessary information in evaluating the patient with a drug eruption. Although the references are very thorough, some drugs list the percentage of patients with a given reaction pattern, but most do not. It is often difficult to tell whether an eruption is very common to a particular drug or quite rare. One of the most difficult consultations asked of dermatologists is the evaluation of a possible drug eruption in the patient receiving multiple medications. In fact, the few medical emergencies dermatologists are asked to see, such as generalized urticaria, toxic epidermal necrolysis, and drug-induced pemphigus, can result in severe morbidity and mortality . This book is an essential tool in allowing the differentiation of the possible drug etiologies to these specific skin reactions.