Drug Metabolizing Enzymes: Cytochrome P450 and Other Enzymes in Drug Discovery and Development

Drug Metabolizing Enzymes: Cytochrome P450 and Other Enzymes in Drug Discovery and Development

by Jae Lee
     
 

Critical in the elimination of drugs and other xenobiotics from the body, cytochrome P450 has strong bearing on scientific assessments of genetic polymorphism in metabolism, possible drug-drug interactions, and bioavailability of candidate drugs. This text systematizes findings on P450 and similar enzymes - as well as parallel issues shaping the pharmaceutical

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Overview

Critical in the elimination of drugs and other xenobiotics from the body, cytochrome P450 has strong bearing on scientific assessments of genetic polymorphism in metabolism, possible drug-drug interactions, and bioavailability of candidate drugs. This text systematizes findings on P450 and similar enzymes - as well as parallel issues shaping the pharmaceutical industry - to promote the next generation of safer, more effective drugs.

Product Details

ISBN-13:
9780824742935
Publisher:
Taylor & Francis
Publication date:
09/28/2003
Pages:
608
Product dimensions:
6.80(w) x 9.70(h) x 1.50(d)

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