Marguerite Gale plays Molly, an Irish colleen who lands a job as a newspaper reporter. Molly's editor assigns her the task of interviewing as many New York theatrical celebrities as possible. She not only accomplishes this task, but takes a record-breaking airplane flight from Connecticut to New York in order to meet her deadline. The raison d'etre for How Molly Made Good was to show off a cornucopia of Broadway luminaries. Among those stage stars making cameo appearances are May Robson, Julia Dean, Henry Kolker, Henrietta Crossman, Mme. Fjorde, Mabel Fenton, and legendary female impersonator Julian Eltinge.