One of the most popular superhero teams in comic book history finally comes to the screen in this big-budget adaptation of the long-running Marvel Comics series. Psychic Professor Xavier (Patrick Stewart) leads a school of skilled mutants called X-Men, a peacekeeping force to safeguard the world against a race of genetically mutated humans known as Homo Sapiens Superior. However, Magneto (Ian McKellen), a mutant with a powerful magnetic charge, has also begun to organize a team to strike first against what he believes to be a threat from humanity. When he kidnaps Rogue (Anna Paquin) from the X-Men's compound, Xavier and his forces must rescue her, even as they continue to vie with Magneto for the fearsomely strong mutant battler Wolverine (Hugh Jackman). Both Xavier and Magneto also have to contend with Senator Kelly (Bruce Davison), a heartless political leader who wants a final solution against mutants on both sides. Fighting for the forces of virtue with the X-Men are Famke Janssen as Jean Grey, Halle Berry as Storm, and James Marsden as Cyclops; Rebecca Romjin-Stamos as Mystique, Ray Park as the Toad, and Tyler Mane as Sabretooth are the minions of Magneto.When a failed assassination attempt occurs on the President's (Cotter Smith) life by the teleporting mutant Nightcrawler (Alan Cumming), it's Professor Xavier (Patrick Stewart) and his School for Gifted Youngsters who are targeted for the crime. While Jean Grey (Famke Janssen) and Storm (Halle Berry) try and locate the assassin, Cyclops (James Marsden) and Xavier (also known as 'Professor X') seek answers from their old foe Magneto (Ian McKellan) in his glass cell...Little do they know they're walking into a trap set by the villainous William Stryker (Brian Cox), a mysterious governmental figure that figures into Wolverine's (Hugh Jackman) secretive past, along with information about the X-Men's operation, supplied by Magneto through a mind-controlling agent. Meanwhile Wolverine, just home from a failed mission to regain his memory, is in charge of the students when a crack-commando team led by Stryker infiltrates the school by order of the President. With a mansion full of young, powerful mutants and the ferocious Wolverine in babysitter mode, can he defend the school against the one man who can answer his questions? What roles do the sinister Mystique (Rebecca Romijn-Stamos) and Lady Deathstrike (Kelly Hu) have in all of this? Why does Stryker want Professor X and his Cerebro machine? With the war between humanity and mutants escalating to extremes, can the rest of the X-Men trust their old foes to help them? Director Bryan Singer returns and raises the stakes in this sequel to the highly lauded 2000 adaptation of Marvel Comics' X-Men.The explosive X-Men motion picture trilogy officially draws to a close with this release that finds Rush Hour director Brett Ratner stepping in for Bryan Singer to tell the tale of a newly discovered mutant "cure," and the polarizing effect it has on mutant/man relations. With the pressure on mutants to give up their powers and pledge alliance with the human race reaching a critical turning point, Professor Charles Xavier (Patrick Stewart) urges tolerance and understanding as his nemesis Magneto (Ian McKellen) gathers a powerful resistance in preparation for the ultimate war against humankind. Hugh Jackman, Halle Berry, Anna Paquin, and James Marsden return to reprise the roles they played in the previous two X-Men films, with Kelsey Grammer and Vinnie Jones joining the cast as Beast and Juggernaut respectively.