Description: This text reviews all the treatments for acute myocardial infarction with proven efficacy, unproven efficacy, and alternative therapy approaches. There are good reviews of thrombolysis, angioplasty, aspirin usage, beta blockade, ACE inhibition, and cholesterol reduction.
Purpose: The purpose is to detail evidence of proven therapies to help improve treatment for acute myocardial infarction.
Audience: This text is directed to those physicians taking care of patients with acute myocardial infarctions. The contributors are often the same physician investigators involved in the trials they write about here.
Features: The majority of the text is directed to treatment of proven efficacy: thrombolysis, coronary angioplasty, aspirin, beta blockade, ACE inhibition, and cholesterol reduction. There are smaller sections of the book devoted to relatively unproven therapy such as nitrates, Heparin anticoagulation, and magnesium. There is a good discussion of the trials comparing urgent invasive approach versus conservative therapy for acute myocardial infarction. The primary drawback is that this publication will necessarily leave out more recent trials of treatment for acute myocardial infarction. The importance of this text is in explaining the data needed to treat our patients more effectively. These treatments need to be used more often.
Assessment: This is a good review of the arsenal of therapies for acute myocardial infarction and the evidence supporting their use. There are several publications on clinical trials available but they either give too brief a listing or take too broad a cardiologic approach. This book has the advantage of a pointed discussion of the trials in question and a review of their place in the spectrum of therapy written by the original investigators.