Elastomeric Proteins: Structures, Biomechanical Properties, and Biological Roles

Elastomeric Proteins: Structures, Biomechanical Properties, and Biological Roles

by Peter R. Shewry
     
 

ISBN-10: 052112848X

ISBN-13: 9780521128483

Pub. Date: 02/04/2010

Publisher: Cambridge University Press

Elastic proteins occur in a wide range of biological systems where they have evolved to fulfill precise biological roles. The best known include proteins in vertebrate muscles and connective tissues, such as titin, elastin, fibrillin and spider silks. Interest in elastomeric proteins is currently high for several reasons. Firstly, they have biological and medical…  See more details below

Overview

Elastic proteins occur in a wide range of biological systems where they have evolved to fulfill precise biological roles. The best known include proteins in vertebrate muscles and connective tissues, such as titin, elastin, fibrillin and spider silks. Interest in elastomeric proteins is currently high for several reasons. Firstly, they have biological and medical significance, particularly in human disease. Secondly, the unusual properties of proteins such as spider silks provide opportunities to develop novel materials. Thirdly, the development of scanning probe microscopy makes it possible to study structures and biomechanical properties of these proteins at the single molecule level.

Product Details

ISBN-13:
9780521128483
Publisher:
Cambridge University Press
Publication date:
02/04/2010
Pages:
416
Product dimensions:
6.00(w) x 8.90(h) x 1.00(d)

Table of Contents

Preface
Contributors
1Functions of Elastomeric Proteins in Animals1
2Elastic Proteins: Biological Roles and Mechanical Properties15
3Elastin as a Self-Assembling Biomaterial39
4Ideal Protein Elasticity: The Elastin Models
5Fibrillin: From Microfibril Assembly to Biomechanical Function94
6Spinning an Elastic Ribbon of Spider Silk115
7Sequences, Structures, and Properties of Spider Silks136
8The Nature of Some Spiders' Silks152
9Collagen: Hierarchical Structure and Viscoelastic Properties of Tendon175
10Collagens with Elastin- and Silk-like Domains189
11Conformational Compliance of Spectrins in Membrane Deformation, Morphogenesis, and Signalling213
12Giant Protein Titin: Structural and Functional Aspects242
13Structure and Function of Resilin259
14Gluten, the Elastomeric Protein of Wheat Seeds279
15Biological Liquid Crystal Elastomers302
16Restraining Cross-Links in Elastomeric Proteins321
17Comparative Structures and Properties of Elastic Proteins338
18Mechanical Applications of Elastomeric Proteins-A Biomimetic Approach352
19Biomimetics of Elastomeric Proteins in Medicine366
Index379

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