Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime

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Overview

With a New Afterword

Must We Age?

Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate ...

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Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime

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Overview

With a New Afterword

Must We Age?

Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach.

In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine’s fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that -damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.

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Editorial Reviews

From the Publisher
“(Dr.) de Grey is hardly just another fountain-of-youth huckster. His it-might-work ideas are based on existing, published, peer-reviewed research. He thinks more like an engineer than a scientist. If even one of his proposals works, it could mean years of extended healthy living.”

—Paul Boutin, The Wall Street Journal

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Product Details

  • ISBN-13: 9780312367077
  • Publisher: St. Martin's Press
  • Publication date: 10/14/2008
  • Edition description: First Edition
  • Edition number: 1
  • Pages: 448
  • Sales rank: 300,154
  • Product dimensions: 6.10 (w) x 9.20 (h) x 1.30 (d)

Meet the Author

Aubrey de Grey, Ph.D., is chairman and chief science officer of the Methuselah Foundation, and editor-in-chief of Rejuvenation Research, the only peer-reviewed academic journal focusing on intervention in aging. He has formulated a wide-ranging plan for the comprehensive and eventually indefinite postponement of age-related physical and mental decline, named SENS (Strategies for Engineered Negligible Senescence). He is the organizer of an ongoing series of conferences and workshops that focus on the key biomedical research relevant to SENS, and he also oversees the Methuselah Foundation’s growing sponsorship of SENS research worldwide.

Michael Rae is Dr. de Grey’s research assistant. He is a longtime member and onetime board member of the Calorie Restriction Society, a main contributor to the society’s “How-to Guide,” and a core scientific investigator with the society’s Cohort Study, which seeks to document the feasibility of calorie restriction in humans and the potential human translatability of the anti-aging effects observed in laboratory organisms.

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Table of Contents


Preface xi Part 1 1
1 The Eureka Moment 3
2 Wake Up-Aging Kills! 7
3 Demystifying Aging 16
4 Engineering Rejuvenation 32 Part 2 47
5 Meltdown of the Cellular Power Plants 49
6 Getting Off the Grid 77
7 Upgrading the Biological Incinerators 101
8 Cutting Free of the Cellular Spider Webs 134
9 Breaking the Shackles of AGE 164
10 Putting the Zombies to Rest 200
11 New Cells for Old 238
12 Nuclear Mutations and the Total Defeat of Cancer 274 Part 3 309
13 Getting from Here to There: The War on Aging 311
14 Bootstrapping Our Way to an Ageless Future 325
15 War Bonds for the Campaign Against Aging 335 Afterword 340 Notes 379 Glossary 405 Index 421
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Customer Reviews

Average Rating 4.5
( 6 )
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Sort by: Showing all of 7 Customer Reviews
  • Posted September 12, 2009

    I hope de Grey's ideas work!

    This book reviews ways to reverse the aging damage in our bodies. I am not an expert and so cannot comment on whether this book is accurate or authoritative. However, I really hope that someone finds ways to do what de Grey suggests. The book's science is extremely interesting, and, at least to a layman, the book is well worth reading for that alone.
    I have a couple of regrets about this book, however. One is that the method de Grey suggests for ending the threat of cancer, would also end male fertility forever. De Grey doesn't seem to mind this. I sure would, however. My second regret is that throughout the book, de Grey comes across as a con artist or snake oil salesman. I know that the journal Nature bothered to review this book; I believe de Grey is telling the truth when he says he has been a scientist. But I don't know what to think about his fundamental honesty and reliability. I would hesitate greatly before sending money to his Methuselah foundation, even though I dearly want aging cured as soon as possible.

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  • Posted March 2, 2009

    Compelling

    Dr. de Grey's book is a compelling call to research and implementation of medical techniques that can potentially lengthen life and improve quality through those years. Although he considers the aspects of aging he addresses comprehensive (and they are each important), he neglects the grosser aspects of aging: arthritic deformities, loss of teeth, skin changes, organ distortion and enlargement and hormonal changes. It is nevertheless an important and exciting treatment of the frontier of age management medicine.

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    Posted January 8, 2011

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    Posted July 29, 2012

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    Posted September 29, 2010

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    Posted December 23, 2012

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