Endocrinology: 3-Volume Set / Edition 5

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Overview

Revised throughout, the 5th Edition of this leading reference presents a complete and up-to-date review and analysis of all aspects of endocrinology, diabetes, and bone metabolism. Readers will also find state-of-the-art information on genetics, proteinomics, and hormone signaling, and coverage of the field's hottest topics in nearly 20 new chapters. Joined by an international team of leading experts—many new to this edition—Drs. Jameson and DeGroot provide guidance that integrates the basic science of endocrinology with clinical medicine and the practical management of endocrine disorders. A clinical focus emphasizes diagnosis and therapy.
  • Features the work of the world's leading authorities—many new to this edition.
  • Organizes information into basic and clinical sections that makes reference quick and easy.
  • Provides tables designed to summarize and organize information, and presents over 1,400 illustrations that clarify complex concepts.
  • Examines the hottest topics in the field today through 19 new chapters including Endocrinology: Impact on science and medicine · Application of genomics and proteinomics to endocrinology · Genetic syndromes in endocrinology · Genetics and syndromes of obesity · Role of the adipocyte in metabolism and endocrine function · Genetic Defects and Disorders of Bone · and Adrenal causes of hypercortisolism.
  • Features many new authors, offering fresh perspectives.

The book contains predominantly black-and-white illustrations, with some color illustrations.

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Editorial Reviews

William D. Kerr
This 3rd edition (previous editions 1979 and 1989) is the most comprehensive and definitive single-source, available reference of endocrinology (the study of ductless glands and hormones or, contemporarily, the study of cell-to-cell communication by messenger molecules traversing an extra-cellular space, permitting cellular cooperation, biological diversity, and survival. These books' purpose is to present, traditionally and newly integrated, the accumulated understanding of the human endocrine system and the diseases that emanate from its disordered function. This worthy objective is achieved within a fabric of historical perspective and of extensive, evolving, reliable and tested scientific base, clearly articulated as art and science of endocrinology broadly related to physiological and pathological function. This text is especially valuable to endocrinologists (fellows, clinicians, researchers, and teachers), internists, other specialists, and medical school, hospital and departmental libraries world-wide. The 246 international authors and editors, each an accomplished researcher or acknowledged teacher, are credible experts in their fields. These scholarly, eminently readable books have a distinguished appearance. The 160 concise, thorough chapters, relating to nine traditional and six nonclassical endocrine organs and their secretions, are complementary and seldom redundant. The table of contents provides an excellent scheme for organizing contemporary molecular endocrinology, for presenting gland physiology and dysfunction, and for integrating endocrine aspects of important functions such as reproduction, feeding, obesity, and aging. There is reasoned emphasis on illustrations,figures, and/or tables to clarify each topic, leading to enhanced understanding and retention of material. These books are essential for endocrinologists, academicians, and medical libraries as the definitive reference work, enhancing initial and continued endocrinological education, practice, and discovery. This new edition is needed to present extensive new material and to serve as framework for understanding, judging, and synthesizing further developments in endocrinology.
Booknews
Second edition of a standard reference work. Revised from the 1979 edition. New topics include: interleukins, hormonal mediators of inflammation in chemotaxis; hormones controlling blood production; hormonal regulation of appetite. Three volumes contain authoritative studies on: principles of hormone actions; the pituitary, neuroendocrinology; thyroid gland; parathyroids; pancreas; adrenal cortex; catecholamines and adrenal medulla; sexual differentiation and puberty; reproductive function in the female; endocrinology of pregnancy; the male reproductive system; multihormonal systems and disorders. Over 1230 illustrations. Extensive references. A fine companion to DeGroot's Thyroid. Annotation c. Book News, Inc., Portland, OR (booknews.com)
From The Critics
Reviewer: Arthur B. Schneider, MD, PhD (University of Illinois at Chicago)
Description: This is the fourth edition, published after an interval of six years, of this three volume treatise. The number of chapters has increased from 160 to 194, the number of pages have decreased from 3024 to 2621 (in part due to reduced margins and smaller type) and the price bas gone down (!) from $510 to $495. Among the new chapters are ones on diagnostic methods and pharmaceutical therapies.
Purpose: This book provides "one stop shopping" for comprehensive information about endocrinology and coverage spans basic concepts to the most practical applications in the clinical arena. This title uniquely occupies the multivolume, comprehensive endocrine textbook niche. The current edition does not disappoint.
Audience: Practicing endocrinologists, clinical and basic endocrinology investigators, and endocrine fellows are the principal targets of this book. Internists, radiologists, and surgeons will find this to be a reliable primary source. No medical library should be without it.
Features: This book is well organized and achieves its goal of providing comprehensive coverage. In addition to sections devoted to the traditional endocrine organ systems, there are many integrative sections and chapters (e.g., principles of hormone action, immunology and endocrinology). The chapters have been written authoritatively by internationally recognized contributors. A few illustrations in color have been added, but inconveniently placed at the beginning of each volume. Occasionally subjects are found in the text that are not found in the generally extensive index.
Assessment: This new edition has kept pace with new advances and is very welcome. It defines one of the three categories of texts used by endocrinologists, the others being one-volume surveys of endocrinology (e.g., Felig et al.'s Endocrinology and Metabolism, 3rd Edition (McGraw-Hill, 1995)) and focused surveys of specific endocrine systems (e.g., Braverman et al.'s Werner and Ingbar's The Thyroid: A Fundamental and Clinical Text), 8th Edition (Lippincott Williams & Wilkins, 2000)). Although endocrinologists will develop their own styles as to when they will use each source, there is no question that this set is an important contribution, one that establishes the standard for the others.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780721603766
  • Publisher: Elsevier Health Sciences
  • Publication date: 9/13/2005
  • Edition description: Older Edition
  • Edition number: 5
  • Pages: 4144
  • Product dimensions: 9.00 (w) x 11.50 (h) x 5.50 (d)

Table of Contents

I. PRINCIPLES OF HORMONE ACTION

1. Endocrinology: Impact on science and medicine

II. GENOMICS & ENDOCRINOLOGY

2. Hormones and gene expression: basic principles
3. Cell division, differentiation, senescence, and death
4. Appication of genomics and proteinomics to endocrinology
5. Transgenic and genetic animal models
6. Genetic syndromes in endocrinology

III. MECHANISMS OF ENDOCRINE SIGNALING & RESPONSE

7. Control of hormone secretion
8. Hormone signaling via tyrosine kinase receptors
9. Hormone signaling via cytokine receptors
10. Hormone signaling via serine kinase receptors
11. Hormone signaling via G-protein coupled receptors
12. Cyclic AMP signaling pathway
13. Second messenger signaling pathways: Phospholipids and calcium
14. MAP kinase and growth factor signaling pathways
15. Nuclear receptors: Sturcture, function and co-factors

IV. NEUROENDOCRINOLOGY & PITUITARY DISEASE

16. Development of the pituitary
17. Prolactin
18. ACTH
19. Endocrine rhythms and the clock
20. Hypothalamic syndromes
21. Evaluation of hypothalamic and pituitary masses
22. Hypopituitarism
23. Acromegaly
24. Cushing’s Disease and Syndrome
25. Non-functioning ademonas and gonadotrophinomas
26. TSH-producing adenomas
27. Prolactinoma
28. Pituitary surgery
29. Evaluation and management of childhood hypothalamic and pituitary tumors
30. Posterior pituitary, diabetes insipidus, SIADH
31. The pineal gland: basic physiology and clinical implications

V. GROWTH & MATURATION

32. Growth hormone
33. Regulation of GH secretion
34. ICH-I, IGF-BPs, and IFG-II
35. Other growth factors
36. Growth and maturation
37. Growth hormone deficiency in children
38. Growth hormone deficiency in adults

VI. IMMUNOLOGY & ENDOCRINOLOGY

39. Autoimmune endocrine disease
40. Interactions of the Endocrine and Immune Systems
41. Autoimmune polyglandular failure syndromes

VII. OBESITY, ANOREXIA, AND NUTRITION

42. Appetite regulation and thermogenesis
43. Obesity: The problem and its management
44. Genetics and syndromes of obesity (
45. Anorexia Nervosa, Bulimia Nervosa, and other eating disorders
46. Starvation and parenteral

VIII. DIABETES MELLITUS

47. Development of the endocrine pancreas
48. Chemistry and biosynthesis of the islet hormones
49. Secretion and metabolism of insulin
50. Insulin action
51. Glucagon and the glucagon-like peptides
52. Integrated control of energy substrate utilization
53. Role of the adipocyte in metabolism and endocrine function
54. Classification and diagnosis of diabetes mellitus
55. Type 1 (Insulin-dependent) diabetes mellitus: Etiology, pathogenesis, and natural history
56. Type 2 diabetes mellitus: Etiology, pathogenesis, and natural history
57. Hyperglycemia secondary to non-diabetic conditions and therapies
58. Syndromes of insulin resistance and lipodystrophy
59. Metabolic syndrome
60. Treatment of Type 1 diabetes mellitus in adults
61. Ketoacidosis and hyperosmolar coma
62. Hypoglycemia
63. Management of Type 2 diabetes mellitus
64. Management of diabetes in children
65. Pancreatic and islet transplantation
66. Relationship of diabetic control to complications
67. Diabetic oculopathy
68. Diabetic neuropathy
69. Diabetic nephropathy
70. Diabetic foot and vascular complications

IX. PARATHYROID GLAND, CALCIOTROPIC HORMONES & BONE METABOLISM

71. Parathyroid hormone and parathyroid hormone-related peptide
72. Calcitonin
73. Vitamin D
74. Regulation of calcium homeostasis
75. Bone development and remodeling
76. Genetic defects in the parathyroid axis
77. Hyperparathyroidism: Differential diagnosis of
78. Malignancy-associated hypercalcemia
79. Medical treatment of hypercalcemia
80. Surgical management of hypercalcemia
81. Familial hypocalciuric hypercalcemia and other disorders due to calcium-sensing receptor mutations
82. Hypoparathyroidism and pseudohypoparathyroidism
83. Genetic defects in vitamin D metabolism and action
84. Nephrolithiasis
85. Genetic Defects and Disorders of Bone
86. Bone imaging and assessment of bone density
87. Renal osteodystrophy
88. Osteomalacia and rickets
89. Osteoporosis
90. Paget’s Disease of bone

X. THYROID

91. Development of the
92. Thyroid-stimulating hormone and regulation of the thyroid
93. Thyroid hormone formation
94. Thyroid Regulatory
95. Thyroid hormone metabolism
96. Thyroid hormone action
97. Throid function tests: Effects of drugs and disease on the thyroid
98. Thyroid
99. Autoimmune thyroid disease
100. Graves’ Disease
101. Graves’ Ophthalmopathy
102. Other causes of hyperthyroidism
103. Chronic (Hashimoto’s) thyroiditis
104. Subacute and Reidel’s thyroiditis
105. Hypothyroidism and myxedema coma
106. Nonthyroidal illness syndrome
107. Multinodular goiter
108. Iodine defieciency
109. Thyroid nodules and Thyroid
110. Medullary thyroid carcinoma
111. TSH receptor mutations
112. Genetic Defects in Thyroid Hormone Synthesis and Action: Defects in Thyroid Hormone
113. Thyroid Hormone Binding and Variants of Transport Proteins
114. Resistance to thyroid hormone
115. Surgery of the thyroid: Abberant thyroid masses

XI. ADRENAL GLAND AND ADRENAL HORMONES

116. The principles, pathways, and enzymes of human steroidogenesis
117. Glucocorticoid physiology
118. Gulcocorticoid receptors and their mechanisms of action
119. Aldosterone: Secretion and
120. Glucocorticoid therapy
121. Adrenal insufficiency/Cushing’s Disease
122. Adrenal causes of hypercortisolism
123. Generalized Glucocorticoid resistance
124. Congenital adrenal
125. Adrenarche and adrenopause
126. Adrenal imaging and adrenal incidentaloma
127. Adrenal neoplasia
128. Primary mineralocorticoid excess
129. Mineralocorticoid deficiency
130. Pheochromocytoma
131. Adrenal surgery

XII. CARDIOVASCULAR ENDOCRINOLOGY

132. Hormones of the cardiovascular system
133. Hormonal regulation of electrolyte and water metabolism
134. Endocrine changes in CHF
135. Management of lipid disorders
136. Essential hypertension and endorine hypertension
137. Orthostatic hypotension

XIII. ENDOCRINE CHANGES IN CRITICALLY ILL PATIENTS

138. Endocrine aspects of critical care

XIV. REPRODUCTIVE ENDOCRINOLOGY AND SEXUAL FUNCTION

139. GnRH and gonadotropins
140. Gonadal peptides: Inhibins, activins, follistatin, MIS
141. Regulation of gonadotropin synthesis and secretion
142. Genetic basis of sexual differentiation
143. Embryology and control of sex differentiation
144. Endocrinology of sexual maturation
145. Environmental agents and the reproductive system
146. Diagnosis and treatment of disorders of sexual development
147. Precocious puberty
148. Delayed puberty
149. Gender identity and sexual behavior

XV. FEMALE REPRODUCTION

150. Folliculogenesis, ovulation, and luteogenesis
151. Ovarian hormone synthesis and secretion
152. Estrogen and progesterone action
153. Hormonal regulation of the menstrual cycle and mechanisms of ovulation
154. Amenorrhea, anovulation, and dysfunctional uterine bleeding
155. Endometriosis
156. Female infertility: Evaluation and management
157. Polycystic ovarian syndrome, hirsutism, and hyperandrogenism
158. Ovulation induction and assisted reproduction
159. Contraception
160. Female sexual dysfunction
161. Premenstual syndrome
162. Mechanisms of menopause and the menopausal transition
163. Ovarian tumors with endocrine manifestations

XVI. ENDOCRINOLOGY OF THE BREAST

164. Hormonal control of the breast development
165. Benign breast disorders
166. Breast cancer and hormonal mangement

XVII. MALE REPRODUCTION

167. Spermatogenesis and regulation of testicular function
168. Androgens and androgen action
169. Androgen receptors and androgen insensitivity syndromes
170. Androgen deficiency disorders
171. Cryptorchidism and hypospadias
172. Male infertility
173. Male sexual dysfunction
174. Male contraception
175. Testicular tumors with Endocrine Manifestations
176. Use and abuse of anabolic steroids
177. Gynecomastia
178. Physiology and pathophysiology of androgenetic alopecia
179. Endocrinology of the Prostate and Benign Prostatic Hyperplasia
180. Prostate cancer

XVIII. ENDOCRINOLOGY OF PREGNANCY

181. Implantation and placental physiology
182. Placental hormones
183. Fetal and neonatal endocrinology
184. Fuel homeostasis in the fetus and neonate
185. Endocrinology of partuition
186. Diabetes mellitus and pregnancy
187. Diagnosis and treatment of thyroid disease during pregnancy
188. Lactation
189. Gestational trophoblastic neoplasms
190. Hormonal changes and endocrine testing in pregnancy

XIX. ENDOCRINE TUMOR SYNDROMES

191. Multiple endocrine neoplasia Type 1
192. Multiple endocrine neoplasia Types IIa and IIb
193. Gastrointestinal hormones and tumor syndromes
194. Carcinoid syndrome
195. Ectopic hormone syndromes

XX. ENDOCRINE TESTING AND ENDOCRINE DRUG

196. Endocrine testing

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