Description: Because of advances in the management of childhood malignancies, the majority of children treated for cancer survive into adulthood. This book describes the treatment-related endocrinopathies that occur over time in these patients.
Purpose: The purpose is to discuss the endocrinopathies that result from childhood cancer and its treatments, including the pathophysiology, investigative and management protocols, and follow-up strategies. The authors examine the evidence base while looking at controversies. Although there are many review articles on the subject, this comprehensive textbook is an important addition to the field.
Audience: It is aimed at clinicians who take care of long-term cancer survivors, including endocrinologists, oncologists, and general practitioners, and it fulfills that purpose. The authors have done research in the topics they discuss and many are recognized authorities in their fields.
Features: The book covers a multitude of endocrine late effects, including hypopituitarism, obesity/metabolic disorders, bone health, and testicular and ovarian function. What is notably missing, however, is a chapter on thyroid disorders, including hypothyroidism and thyroid nodules and cancer. Strengths include discussions about normal physiology, limitations of diagnostic testing, limitations of research studies to date, assessment of evidence, and future directions.
Assessment: Due to its comprehensive review of the literature and assessment of the evidence, this is a high quality book. It should be a part of the library of any clinician taking care of survivors of childhood cancer.