Environmental Health Risk Assessment for Public Health / Edition 1

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Written by experts in the field, this important book provides an introduction to current risk assessment practices and procedures and explores the intrinsic complexities, challenges, and controversies associated with analysis of environmental health risks.

Environmental Health Risk Assessment for Public Health offers 27 substantial chapters on risk-related topics that include:

  • What Is Risk and Why Study Risk Assessment
  • The Risk Assessment–Risk Management Paradigm
  • Risk Assessment and Regulatory Decision-Making in Environmental Health
  • Toxicological Basis of Risk Assessment
  • The Application of PBPK Modeling to Risk Assessment
  • Probabilistic Models to Characterize Aggregate and Cumulative Risk
  • Molecular Basis of Risk Assessment
  • Comparative Risk Assessment
  • Occupational Risk
  • Radiological Risk Assessment
  • Microbial Risk Assessment
  • Children’s Risk Assessment
  • Life Cycle Risk
  • Environmental Laws and Regulations
  • Precautionary Principles
  • Risk Communication
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Editorial Reviews

Doody's Review Service
Reviewer: J. Thomas Pierce, MBBS PhD(Navy Environmental Health Center)
Description: As a matter of background, the Environmental and Occupational Health Council selected risk assessment as a 2004 topic. Sixteen significant chapters and 11 intriguing case studies emerged. Thus, risk assessment relevant to environmental health becomes a topic sufficient to warrant publication sponsorship by the Association of Schools of Public Health.
Purpose: The editors and authors reason that risk assessment is an important part of the training of environmental and occupational health students as well as others studying toxicology and environmental medicine and engineering. In its broadest context, risk assessment is the penultimate task facing not only scientists but our citizenry.
Audience: This book will find broad adoption throughout public health programs, but I encourage a broader readership among scientific and policy audiences. Neither its mathematics nor its biology is at all exclusionary.
Features: The 11 case studies address multiple contaminants and pathways, intraspecies differences (acrylonitrile), rocket fuel contamination (perchlorate anion), asthmagens and endocrine disruptors affecting young and old, swimming pool issues, U-shaped dose-response relationships, ecosystem (river) risk assessments and comparative and community risk analyses. Readers could start with one or more case studies, reasoning whether they agree with the authors' findings and then return to the 16 didactic chapters for review.
Assessment: The authors and editors have done a good job of summarizing tools that stretch along a continuum beginning with molecules and receptors, stretching through regulations and modeled frameworks and extending to multiple species and even populations. A risk assessor routinely probably uses about a half dozen of the techniques outlined in the 16 chapters, depending upon his/her interests. What sets this book apart are its thought questions coupled with interesting case studies. Every reader will react a little differently, but mention of communities such as Triana (Alabama) or the Neuse River Estuary (North Carolina) or terms such as toxicokinetics and gene expression will generate powerful images. This book can encourage newcomers learning the art and science of risk assessment as well as the more experienced to perfect its process and outcome.
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Product Details

  • ISBN-13: 9780787983192
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 2/16/2007
  • Series: Public Health/Environmental Health Series, #1
  • Edition description: REV
  • Edition number: 1
  • Pages: 664
  • Product dimensions: 7.30 (w) x 9.45 (h) x 1.88 (d)

Meet the Author

Mark G. Robson, Ph.D., M.P.H., is director of the New Jersey Agricultural Experiment Station and profesor of entomology at Rutgers University, School of Environmental and Biological Sciences, New Brunswick, New Jersey.

William A. Toscano, Ph.D., is professor and division head, Environmental and Occupational Health, University of Minnesota School of Public Health, Minneapolis, Minnesota.

The Association of Schools of Public Health (ASPH), sponsor, is the only national organization representing the deans, faculty, and students of the CEPH accredited schools of Public Health in the United States and Mexico.

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Table of Contents

Figures, Tables, and Exhibits xi

Preface xvii

About the Editors xxi

About the Contributors xxiii

1 Introduction to Risk Assessment in Public Health 1
Mark Robson and Fred Ellerbusch

2 The Risk Assessment–Risk Management Paradigm 11
Gilbert S. Omenn

3 Risk Assessment and Regulatory Decision Making in Environmental Health 31
Felicia Wu and William H. Farland

4 Toxicological Basis for Risk Assessment 55
Tee L. Guidotti and Marina S. Moses

5 The Application of Physiologically Based Pharmacokinetic (PBPK) Modeling to Risk Assessment 85
Raymond S. H. Yang and Yasong Lu

6 Probabilistic Models for Characterizing Aggregate and Cumulative Risk 121
John L. Adgate and Gurumurthy Ramachandran

7 Molecular Tools for Risk Assessment 155
William A. Toscano and Chisato Mori

8 Comparative Risk Assessment 173
Michele Morrone

9 Risk in the Workplace: Where Analysis Began and Problems Remain Unsolved 187
Adam M. Finkel and P. Barry Ryan

10 Radiological Risk Assessment 239
Ronald O. Rahn and Arthur C. Upton

11 Microbial Risk Assessment 285
Rebecca T. Parkin

12 Children’s Risk Assessment 315
Natalie C. G. Freeman

13 Biological Monitoring of Exposure to Environmental Chemicals Throughout the Life Stages: Requirements and Issues to Consider for Birth Cohort Studies 345
Dana B. Barr, Richard Y. Wang, and Larry L. Needham

14 Overview of Environmental Public Health Laws and Their Relation to Risk 383
Russellyn S. Carruth and Bernard D. Goldstein

15 Why Risk Assessment Is Not Enough to Protect Health: Rationale for a Precautionary Approach to Science and Policy 423
Joel A. Tickner

16 Risk Communication 463
Susan L. Santos


17 Improvement of Risk Assessments for Multicontaminant Sites in the Face of Critical Data Gaps 489
Yoram Cohen and Adrienne Katner

18 Intraspecies Differences in Acute Acrylonitrile Toxicity 511
Gwendolyn Ball, Clif McLellan, and Lori Bestervelt

19 Drinking Water Contamination by Perchlorates from Department of Defense Rocket Fuel Facilities 517
Terry Gratton and Norman Trieff

20 Multi-Pathway Risk Assessment for Children Living Near a Hazardous Waste Site 523
Serap Erdal

21 Child with Asthma Living in a Moisture-Damaged Home 531
Myrtis Sullivan

22 Endocrine Disruption Through Phthalates/Plasticizers 541
Christine Ziebold

23 Estimation of Health and Safety Risks from Exposure to Chlorine and Chloroform for Swimmers in Pools 547
Richard P. Hubner

24 U-Shaped Dose-Response Curve for Risk Assessment of Essential Trace Elements: Copper as a Case Study 555
Bonnie Ransom Stern

25 Ecosystem Risk Assessment: The Neuse River Estuary, North Carolina 563
Craig A. Stow, Mark E. Borsuk, and Kenneth H. Reckhow

26 The Ohio Comparative Risk Project 587
Michele Morrone

27 Community-Based Risk Assessment: DDT Contamination in Triana, Alabama 597
Padma Tadi-Uppala

Name Index 605

Subject Index 611

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