Environmental Impacts on Reproductive Health and Fertility

Environmental Impacts on Reproductive Health and Fertility

by Tracey J. Woodruff
     
 

ISBN-10: 0521519527

ISBN-13: 9780521519526

Pub. Date: 03/31/2010

Publisher: Cambridge University Press

Many reproductive and developmental health problems are caused by exposure to chemicals that are widely dispersed in our environment. These problems include infertility, miscarriage, poor pregnancy outcomes, abnormal fetal development, early puberty, endometriosis, and diseases and cancers of reproductive organs. The compelling nature of the collective science has

Overview

Many reproductive and developmental health problems are caused by exposure to chemicals that are widely dispersed in our environment. These problems include infertility, miscarriage, poor pregnancy outcomes, abnormal fetal development, early puberty, endometriosis, and diseases and cancers of reproductive organs. The compelling nature of the collective science has resulted in recognition of a new field of environmental reproductive health. Focusing on exposures to environmental contaminants, particularly during critical periods in development and their potential effects on all aspects of future reproductive life-course, this book provides the first comprehensive source of information bringing together the arguments that are spread out among various scientific disciplines in environmental health, clinical and public health fields. It provides a review of the science in key areas of the relationship between environmental contaminants and reproductive health outcomes, and recommendations on efforts toward prevention in clinical care and public policy.

Product Details

ISBN-13:
9780521519526
Publisher:
Cambridge University Press
Publication date:
03/31/2010
Pages:
262
Product dimensions:
7.60(w) x 9.70(h) x 0.70(d)

Table of Contents

List of contributors vii

Preface xi

1 Introduction Tracey J. Woodruff Linda C. Giudice 1

2 Environmental contaminants and exposure Mary A. Fox Yutaka Aoki 8

3 Development and maturation of the normal female reproductive system 23

3.1 Ovary Laxmi A. Kondapalli Teresa K. Woodruff 23

3.2 Oviduct and uterus Leo F. Doherty Hugh S. Taylor 29

3.3 Breast Maricel V. Maffini Carlos Sonnenschein Ana M. Soto 36

4 Development and maturation of the normal male reproductive system Richard M. Sharpe 48

5 Modern genetics of reproductive biology Taisen Iguchi Shinichi Miyagawa Tamotsu Sudo 60

6 Mechanisms of endocrine disruption K. Leigh Greathouse Cheryl L. Walker 72

7 Developmental exposures and implications for early and latent disease Retha R. Newbold Jerrold J. Heindel 92

8 Wildlife as sentinels of environmental impacts on reproductive health and fertility Heather J. Hamlin Louis J. Guillette 103

9 Environmental contaminants and effects on timing and progression of human pubertal development Annette Mouritsen Julie Damm Lise Aksglaede Kaspar Sørensen Anders Juul 115

10 Environmental contaminants and impacts on healthy and successful pregnancies Rémy Slama Sylvaine Cordier 125

11 Environmental contaminants and the reproductive and fertility effects in the male 145

11.1 Introduction Sarah J. Janssen 145

11.2 Possible role of fetal exposure Jorma Toppari Helena E. Virtanen Niels E. Skakkebaek 147

11.3 Adult exposure and effects on fertility John D. Meeker Russ Hauser 154

12 Environmental contaminants, female reproductive health and fertility Pauline Mendola Germaine M. Buck Louis 161

13 Environmental contaminants and related systems that have implications for reproduction 173

13.1 The neuroendocrine system Andrea C. Gore 173

13.2 The thyroid system R. Thomas Zoeller John D. Meeker 180

13.3 The immune system Robert W. Luebke Dori R. Germolec 188

14 Environmental contaminants and cancers of the reproductive tract Gail S. Prins Esther L. Calderon 194

15 Communicating with patients and the public about environmental exposures and reproductive risk Gina M. Solomon Sarah J. Janssen 214

16 Interpreting science in the policy context Tracey J. Woodruff Sarah J. Janssen 227

17 Conclusions–what does all this mean, and where are we going? Shanna H. Swan Patricia Hunt Linda C. Giudice 240

Index 243

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