Environmental Stressors in Health and Disease / Edition 1

Environmental Stressors in Health and Disease / Edition 1

by Jurgen Fuchs, Lester Packer, Fuchs Fuchs
     
 

ISBN-10: 0824705300

ISBN-13: 9780824705305

Pub. Date: 07/28/2001

Publisher: Taylor & Francis

This volume illustrates the impact of environmental oxidants on the tissues of the eyes, lungs and skin, as well as on the immune system - highlighting common illnesses, injuries and pathologies induced by pro-oxidant environmental xenobiotics such as inflammation, immune response, signal transduction, regulation of gene expression, and carcinogenesis. It provides

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Overview

This volume illustrates the impact of environmental oxidants on the tissues of the eyes, lungs and skin, as well as on the immune system - highlighting common illnesses, injuries and pathologies induced by pro-oxidant environmental xenobiotics such as inflammation, immune response, signal transduction, regulation of gene expression, and carcinogenesis. It provides clinical presentations and discusses the effects of environmental oxidants on target organs.

Product Details

ISBN-13:
9780824705305
Publisher:
Taylor & Francis
Publication date:
07/28/2001
Series:
Oxidative Stress and Disease Series
Edition description:
New Edition
Pages:
528
Product dimensions:
6.25(w) x 9.25(h) x 1.00(d)

Table of Contents

Series Introduction
Preface
Contributors
IMolecular and Cellular Aspects of Prooxidant Environmental Xenobiotics
1Free Radical Reactions in Human Disease1
2Radicals and Inflammation: Mediators and Modulators17
3Autoimmunity Caused by Oxidizing Foreign Compounds53
4Role of Oxidative Stress in Chemical Carcinogenesis81
5Proposed Mechanisms of Arsenic Toxicity Carcinogenesis103
6Redox Regulation of Gene Expression and Transcription Factors in Response to Environmental Oxidants115
IITarget Organs of Environmental Oxidants: Lung
7Cigarette Smoking and Pulmonary Oxidative Damage135
8Health Effects of Diesel Exhaust and Diesel Exhaust Particles157
9The Role of Free Radicals in Asbestos- and Silica-Induced Fibrotic Lung Diseases185
10Reactive Oxygen Species and Silica-Induced Carcinogenesis203
11Atmospheric Oxidants and Respiratory Tract Surfaces225
IIITarget Organs of Environmental Oxidants: Skin
12Redox Modulation and Oxidative Stress in Dermatotoxicology237
13Dermatotoxicology of Environmental and Occupational Chemical Hazards: Agents and Action271
14Photooxidative Stress in Skin and Regulation of Gene Expression319
15Ozone Stress in the Skin Barrier335
16Immunotoxicity in Environmental Agents in the Skin345
IVTarget Organs of Environmental Oxidants: Eye
17Environmental Stressors and the Eye365
18Free Radicals and Aging of Anterior Segment Tissues of the Eye381
19The Role of Ocular Free Radicals in Age-Related Macular Degeneration423
20Nutritional Influences on Risk for Cataract457
Index489

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