Enzybiotics: Antibiotic Enzymes as Drugs and Therapeutics / Edition 1

Enzybiotics: Antibiotic Enzymes as Drugs and Therapeutics / Edition 1

by Tomas G. Villa
     
 

Enzybiotics, by using enzymes to fight bacteria, offer a novel and promising new way to combat infectious diseases. This book presents the state-of-the-art and therapeutic potential of enzybiotics, with a stress on therapeutic applications. The coverage offers a unique combination of medicinal chemistry, microbiology, genetics, and biochemistry. It also addresses

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Overview

Enzybiotics, by using enzymes to fight bacteria, offer a novel and promising new way to combat infectious diseases. This book presents the state-of-the-art and therapeutic potential of enzybiotics, with a stress on therapeutic applications. The coverage offers a unique combination of medicinal chemistry, microbiology, genetics, and biochemistry. It also addresses the timely topic of bacterial resistance to antibiotics, and provides readers with a novel angle to study and combat infectious diseases.

Product Details

ISBN-13:
9780470376553
Publisher:
Wiley
Publication date:
01/07/2010
Pages:
284
Product dimensions:
6.30(w) x 9.30(h) x 1.00(d)

Table of Contents

PREFACE.

CONTRIBUTORS.

1 ENZYBIOTICS AND THEIR POTENTIAL APPLICATIONS IN MEDICINE (Jan Borysowski and Andrzej Górski).

2 ADVANTAGES AND DISADVANTAGES IN THE USE OF ANTIBIOTICS OR PHAGES AS THERAPEUTIC AGENTS (Patricia Veiga-Crespo and Tomas G. Villa).

3 ENZYBIOTICS AS SELECTIVE KILLERS OF TARGET BACTERIA (Juan C. Alonso and Marcelo E. Tolmasky).

4 PHYLOGENY OF ENZYBIOTICS (Patricia Veiga-Crespo and Tomas G. Villa).

5 BACTERIOPHAGE LYSINS: THE ULTIMATE ENZYBIOTIC (Vincent A. Fischetti).

6 BACTERIOPHAGE HOLINS AND THEIR MEMBRANEDISRUPTING ACTIVITY (María Gasset).

7 ANTI-STAPHYLOCOCCAL LYTIC ENZYMES (Jan Borysowski and Andrzej Górski).

8 MEMBRANE-TARGETED ENZYBIOTICS (María Gasset).

9 DESIGN OF PHAGE COCKTAILS FOR THERAPY FROM A HOST RANGE POINT OF VIEW (Lawrence D. Goodridge).

10 IDENTIFYING PHAGE LYTIC ENZYMES: PAST, PRESENT, AND FUTURE (Jonathan E. Schmitz, Raymond Schuch, and Vincent A. Fischetti).

11 USE OF GENETICALLY MODIFIED PHAGES TO DELIVER SUICIDAL GENES TO TARGET BACTERIA (Lawrence D. Goodridge).

CONCLUDING REMARKS: THE FUTURE OF ENZYBIOTICS (Patricia Veiga-Crespo and Tomas G. Villa).

INDEX.

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