BN.com Gift Guide

Enzyme Kinetics: Principles and Methods / Edition 2

Hardcover (Print)
Used and New from Other Sellers
Used and New from Other Sellers
from $163.33
Usually ships in 1-2 business days
(Save 34%)
Other sellers (Hardcover)
  • All (5) from $163.33   
  • New (4) from $163.33   
  • Used (1) from $179.82   

Overview

This new, expanded and updated edition of the user-friendly and comprehensive treatise on enzyme kinetics expertly balances theory and practice. This is an indispensable aid for advanced students and professionals working with enzymes, whether biochemists, biotechnologists, chemical biologists, pharmacologists or bioengineers in academia, industry and clinical research.

Read More Show Less

Editorial Reviews

From the Publisher
“Overall, this is an excellent and thorough treatment of a difficult subject. As well as appealing to biochemists, there are also elements of interest to those studying pharmacology and the pharmacokinetic distribution of drugs. The mathematical nature and advanced coverage means that it is most suitable for researchers who already have a strong grounding in the subject. I will certainly be consulting it during my research.” (Biochemist, 29 May 2013)

“This new, expanded and updated edition of the user–friendly and comprehensive treatise on enzyme kinetics expertly balances theory and practice. This is an indispensable aid for advanced students and professionals working with enzymes, whether biochemists, biotechnologists, chemical biologists, pharmacologists or bioengineers in academia, industry and clinical research.” (Biology Community, 29 November 2012)

Enzyme kinetics is not a new area in biochemistry. Thirty years ago, enzyme kinetics was one of the most important tools for deconstructing enzymatic mechanisms. With advances in enzyme structure determination and molecular genetics, enzyme kinetics is no longer as prominent. However, enzyme kinetics is still useful to gain insight into enzymes that are too large for NMR studies and that cannot be crystallized. Many enzymes that fit into this category are membrane bound, the kinetics of which are much more complicated. In this new edition (1st ed., 2002), Bisswanger (Univ. of Tübingen, Germany) does a nice job of extending solution enzyme kinetics to membrane-bound enzymes. Setting it apart from other works on the subject, Enzyme Kinetics does not simply deal with substrate binding as a part of the reaction kinetics, but instead devotes about one-third of the text to equilibrium binding between macromolecules and ligands in which no reaction catalysis follows the binding. This binding is then directly connected with enzyme catalyzed reaction kinetics. Enzyme Kinetics was written to serve as a graduate-level course resource and would serve this population well. The inclusion of student problems would be an improvement. Summing Up: Recommended. Graduate students, researchers, and faculty. — L. J. Liotta, Stonehill College (Choice, February 2009)

From The Critics
By applying techniques to pursue rapid kinetic reactions it is possible to separate a complete reaction into different time segments and to determine the rate constants of individual steps of the reaction. The author demonstrates the methods by which this is done and explains the theory behind it. Topics include reversible enzyme reactions, enzyme inhibition, multi-substrate reactions, special enzyme mechanisms, and isotope exchange. Specific methods detailed include electrochemical methods, calorimetry, and spectroscopy. The CD-ROM contains a graphics-plotting program intended as a companion to the book. Translated from the third edition of the German work Theorie und Methoden/>. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Read More Show Less

Product Details

  • ISBN-13: 9783527319572
  • Publisher: Wiley
  • Publication date: 5/27/2008
  • Edition description: Second, Revised and Updated Edition
  • Edition number: 2
  • Pages: 320
  • Product dimensions: 7.03 (w) x 9.72 (h) x 0.83 (d)

Meet the Author

Prof. Dr. Hans Bisswanger is currently at the Interfaculty Institute of Biochemistry at the University of Tübingen. He has developed and leads an intensive course on enzyme kinetics, enzyme technology and ligand binding, while his main focus is on structural and regulatory mechanisms of multi-enzyme complexes and temperature stable enzyme complexes. He is also working on the gentle immobilization of enzyme activities on synthetic surfaces, a method which has been favorably applied for the restoration of damaged documents.

Read More Show Less

Table of Contents

Symbols and Abbreviations
Introduction
Multiple Equilibria
- Diffusion
- Interaction of ligands with macromolecules o Macromolecules with identical, non-identical, independent and interacting binding sites
Enzyme Kinetics
- reaction order
- kinetics,
o analysis of kinetic data, enzyme inhibition, multi-substrate reactions,
o analysis of complex enzyme mechanisms, allosteric enzymes,
- PH, temperature dependence of enzymes
- Isotope exchange
- Statistical methods in enzyme kinetics
Methods
- methods for the investigation of multiple equilibria, electrochemical methods, spetroscopy, calorimetry, measurements of fast reactions
Index

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)