Eosinophils in Allergy and Inflammation

by Gerald J. Gleich (Editor)

Overview

This work presents the proceedings of a conference held at Adare Manor, County Limerick, Ireland. It provides an updated, in-depth review of the biological role of eosinophils in allergic diseases, summarizing basic knowledge of these unique cationic proteins. The book features an annotated discussion of the conference's post-presentation question-and-answer session.

Product Details

ISBN-13:	9780367455996
Publisher:	CRC Press
Publication date:	11/26/2019
Series:	Clinical Allergy and Immunology
Pages:	528
Product dimensions:	6.00(w) x 9.00(h) x (d)

About the Author

Gerald J. Gleich Mayo Clinic and Mayo Foundation Rochester, Minnesota, A. BarryKay National Heart and Lung Institute London, England

Table of Contents

"Eosinophil Granule Proteins: Structure and Function, Gerald J. Gleich, Dohn G. Glitz, and Randa I. Abu-Ghazaleh Human Eosinophil Lysophospholipase (Charcot-Leyden Crystal Protein): Molecular Cloning, Expression, and Potential Functions in Asthma, Steven J. Ackerman, Mike A. Clark, Zeqi Zhou, Charles G. Irvin, Daniel G. Tenen, and Yuan-Po Tu G-Protein Regulation of Eosinophil Exocytosis, Oliver Cromwell, Bastien D. Gomperts, and Manfred Lindau Regulation of Eosinophil Function by P-Selectin, Mathew A. Vadas, C. M. Lucas, J. R. Gambel, Angel F. Lopez, M. P. Skinner, and M. C. Berndt Structural Basis for the GM-CSF- and IL-3-Mediated Stimulation of Eosinophil Production and Function in Humans, Angel F. Lopez, J. Woodcock, T. Hercus, S. Barry, P. Dyson, P. Simmons, M. F. Shannon, and Mathew A. Vadas The Role of Adhesion Molecules and Cytokines in Eosinophil Recruitment, Robert P. Schleimer, Motohiro Ebisawa, Steve N. Georas, and Bruce S. Bochner The Role of Adhesion in Eosinophil Accumulation and Activation in Asthma, Andrew J. Wardlaw, Garry M. Walsh, A. R. E. Anwar, Adele Hartnell, Andrew M. Bentley, and A. Barry Kay Eosinophil-Active Cytokines in Human Disease: Development and Use of Monoclonal Antibodies to IL-3, IL-5, and GM-CSF, John S. Abrams, Gerald J. Gleich, Robert E. Van Dyke, and Jon E. Silver Ultrastructural Studies on Mechanisms of Human Eosinophil Activation and Secretion, Ann M. Dvorak Eosinophil Differentiation and Cytokine Networks in Allergic Inflammation, Judah A. Denburg, Jerry Dolovich, Jean Marshall, Isabelle Pin, Peter Gibson, Isao Ohno, Susetta Finotto, Fred Hargreave, and Manel Jordana Eosinophil Membrane Receptors: Function of IgE- and IgA-Binding Molecules, Monique Capron, Marie-JosE Truong, Pierre Desreumaux, BouchaIb Lamkhioued, Margherita Tomassini, and AndrE Capron Cytokine Regulation of Eosinophil-Mediated Inflammatory Reactions by Modulation of Eosinophil Programmed Cell Death and Subsequent Priming for Augmented Function, William F. O

Editorial Reviews

From an international conference in Limerick County, Ireland (no date noted) 26 papers explore the mechanisms by which a particular class of peripheral blood leukocyte generates inflammatory toxins that contribute to bronchial asthma, allergies, and probably a whole range of other disorders. They discuss such topics as the structure and function of eosinophil granule proteins, ultrasonic studies on activation and secretion in humans, and immunological reactions. A durable reference for clinicians and researchers. Annotation c. Book News, Inc., Portland, OR (booknews.com)

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