Epigenetics

Be the first to write a review

Overview

Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs and parts that did not pre-exist in the fertilized egg. An exciting and stimulating volume which used the extensive knowledge of basic transcriptional control as a foundation to explore the more complex and interesting level at which genes can be regulated.

Discusses current understanding of molecular mechanisms that ...

See more details below
Available through our Marketplace sellers.
See All Options
Other sellers (Hardcover)
  • All (7) from $13.25   
  • New (4) from $113.00   
  • Used (3) from $13.25   
Close
Sort by
Page 1 of 1
Showing All
Note: Marketplace items are not eligible for any BN.com coupons and promotions
$113.00
Marsarbooks
Seller since 2009

Feedback rating:

(0)

Condition:

New — never opened or used in original packaging.

Like New — packaging may have been opened. A "Like New" item is suitable to give as a gift.

Very Good — may have minor signs of wear on packaging but item works perfectly and has no damage.

Good — item is in good condition but packaging may have signs of shelf wear/aging or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Acceptable — item is in working order but may show signs of wear such as scratches or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Used — An item that has been opened and may show signs of wear. All specific defects should be noted in the Comments section associated with each item.

Refurbished — A used item that has been renewed or updated and verified to be in proper working condition. Not necessarily completed by the original manufacturer.

New
1998 Hard cover New. No dust jacket as issued. Excellent as new condition, mint. A brand new copy. Sewn binding. Cloth over boards. 304+ pages, includes index and illustrations. ... Novartis Foundation Symposium, 214. *****PLEASE NOTE: This item is shipping from an authorized seller in Europe. In the event that a return is necessary, you will be able to return your item within the US. To learn more about our European sellers and policies see the BookQuest FAQ section***** Read more Show Less

Ships from: Cambridge, United Kingdom

Usually ships in 1-2 business days

  • •Canadian
  • •International
  • •Standard, 48 States
  • •Standard (AK, HI)
  • •Express, 48 States
  • •Express (AK, HI)
$113.00
Marsarbooks
Seller since 2009

Feedback rating:

(0)

Condition: New
1998 Hard cover New. No dust jacket as issued. Excellent as new condition, mint. A brand new copy. Sewn binding. Cloth over boards. 304+ pages, includes index and illustrations. ... Novartis Foundation Symposium, 214. *****PLEASE NOTE: This item is shipping from an authorized seller in Europe. In the event that a return is necessary, you will be able to return your item within the US. To learn more about our European sellers and policies see the BookQuest FAQ section***** Read more Show Less

Ships from: Cambridge, United Kingdom

Usually ships in 1-2 business days

  • •Canadian
  • •International
  • •Standard, 48 States
  • •Standard (AK, HI)
  • •Express, 48 States
  • •Express (AK, HI)
$113.00
Marsarbooks
Seller since 2009

Feedback rating:

(0)

Condition: New
1998 Hard cover New. No dust jacket as issued. Excellent as new condition, mint. A brand new copy. Sewn binding. Cloth over boards. 304+ pages, includes index and illustrations. ... Novartis Foundation Symposium, 214. *****PLEASE NOTE: This item is shipping from an authorized seller in Europe. In the event that a return is necessary, you will be able to return your item within the US. To learn more about our European sellers and policies see the BookQuest FAQ section***** Read more Show Less

Ships from: Cambridge, United Kingdom

Usually ships in 1-2 business days

  • •Canadian
  • •International
  • •Standard, 48 States
  • •Standard (AK, HI)
  • •Express, 48 States
  • •Express (AK, HI)
$145.00
bluehouse
Seller since 2013

Feedback rating:

(39)

Condition: New
Brand new.

Ships from: acton, MA

Usually ships in 1-2 business days

  • •Standard, 48 States
Page 1 of 1
Showing All
Close
Sort by
Sending request ...

More About This Book

Overview

Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs and parts that did not pre-exist in the fertilized egg. An exciting and stimulating volume which used the extensive knowledge of basic transcriptional control as a foundation to explore the more complex and interesting level at which genes can be regulated.

Discusses current understanding of molecular mechanisms that direct epigenetic phenomena & future work & solutions.

Read More Show Less

Product Details

  • ISBN-13: 9780471977711
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 4/13/1998
  • Series: Novartis Foundation Symposia Series , #137
  • Edition number: 1
  • Pages: 201
  • Product dimensions: 6.22 (w) x 9.31 (h) x 0.83 (d)

Table of Contents

Introduction 1
Gene silencing by methyl-CpG-binding proteins 6
Discussion 16
DNA methylation, nucleosomes and the inheritance of chromatin structure and function 22
Discussion 35
General discussion I: The methylation of CpG islands 46
Heritable chromatin states induced by the Polycomb and trithorax group genes 51
Discussion 61
The dynamics of globin gene expression and position effects 67
Discussion 79
Multiple epigenetic events regulate mating-type switching of fission yeast 87
Discussion 99
General discussion II: Centromeres 104
Nuclear organization and silencing: trafficking of Sir proteins 114
Discussion 126
Epigenetic mechanisms in the regulation of the maize Suppressor-mutator transposon 133
Discussion 140
Transgene-promoted epigenetic switches of chalcone synthase activity in petunia plants 144
Discussion 154
General discussion III: Nucleolar organization 163
General discussion III: The silencing of endogenous sequences and transgenes 164
Gene silencing in plants: relevance for genome evolution and the acquisition of genomic methylation patterns 168
Discussion 181
The host defence function of genomic methylation patterns 187
Discussion 195
Mammalian X chtomosome inactivation 200
Discussion 209
Methylation dynamics, epigenetic fidelity and X chromosome structure 214
Discussion 225
General discussion IV: Does DNA methylation regulate gene activity? 228
Imprinting and gene silencing in mice and Drosophila 233
Discussion 244
Making sense of imprinting the mouse and human IGF2R loci 251
Discussion 260
Imprinted genes in the Prader-Willi deletion 264
Discussion 275
Final general discussion: Rules of DNA methylation in humans inferred from the fragile X gene, FMRI 280
Summary 291
Index of contributors 293
Subject index 295
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Review Guidelines
Add Recommendations
Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously
    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)