Table of Contents
Contributor List ix Series Foreword xiii
Preface xv
Part I: Epilepsy Basics
1 Recognizing Seizures and Epilepsy: Insights from Pathophysiology 3 Carl E. Stafstrom
2 Classifying Epileptic Seizures and the Epilepsies 10 Valeria M. Muro and Mary B. Connolly
3 What Causes Epilepsy? 15 Anna Rosati and Renzo Guerrini
4 Epidemiology of Seizures and Epilepsy 28 Aidan Neligan and Josemir W. Sander
Part II: Working up Seizures and Epilepsy
5 Diagnosing and Localizing Seizures at the Bedside and in Clinic 35 Joseph I. Sirven
6 Psychogenic Nonepileptic Episodes 42 Vaishali S. Phatak
7 What Can the EEG Tell Us? 45 Mark Quigg
8 What Can Neuroimaging Tell Us? 54 Edward J. Novotny
9 Workup of New-Onset Seizures 61 Jennifer Langer
10 Evaluation of the Patient with Medically Refractory Epilepsy 67 Gregory L. Holmes
Part III: Using Antiepileptic Medications
11 Choosing, Initiating, Adjusting, and Changing Antiepileptic Medications 77 John W. Miller
12 Antiepileptic Drug Adverse Effects: What to Watch Out For 84 Jacquelyn L. Bainbridge and Caleb Y. Oh
13 Antiepileptic Drug Interactions 91 Philip N. Patsalos
14 Recognizing Intractability to Antiepileptic Medication 102 Bassel W. Abou-Khalil
15 Optimizing Antiepileptic Drug Therapy in Refractory Epilepsy 107 Nicholas P. Poolos
16 Rescue Medications for Home Treatment of Acute Seizures 112 Peter Wolf and Rûta Mameniškienë
17 When and How to Stop Antiepileptic Drugs 118 John D. Hixson
18 Using Parenteral Antiepileptic Medications 122 Jane G. Boggs
19 Pharmacopeia 126 Gail D. Anderson
Part IV: Special Topics in Pediatric Epilepsy
20 Seizures in the Neonate 141 Adam L. Hartman and Frances J. Northington
21 Benign and Malignant Childhood Epilepsies 147 Katherine C. Nickels and Elaine C. Wirrell
22 Epilepsy: When to Perform a Genetic Analysis 159 Heather E. Olson and Annapurna Poduri
23 Metabolic Disorders Not to Miss 167 Phillip L. Pearl and Yuezhou Joe Yu
Part V: Special Topics in Adult Epilepsy
24 Juvenile Myoclonic Epilepsy and Other Primary Generalized Epilepsies 177 Shahin Hakimian
25 Epilepsy in Women of Childbearing Age 184 Autumn Klein
26 Epilepsy After Sixty 189 Edward Faught
Part VI: What can be done when medication doesn’t work?
27 When Should Epilepsy Neurosurgery Be Considered, and What Can It Accomplish? 199 Paul A. Garcia
28 When Should Vagus Nerve Stimulation Be Considered, and What Can It Accomplish? 205 Pearce J. Korb and Sandra L. Helmers
29 Ketogenic Diet and Alternative Therapies 210 Dana Ekstein and Steven C. Schachter
Part VII: How are acute seizures and status epilepticus evaluated and treated in the emergency department and the hospital?
30 acute Symptomatic Seizures in Children and Adults: Evaluation and Treatment 217 J. Stephen Huff and Jessica L. Carpenter
31 Evaluating and Treating Status Epilepticus 222 Jeffrey Bolton and Howard P. Goodkin
32 Recognizing, Assessing, and Treating Seizures and Status Epilepticus in the ICU 227 Nicolas Gaspard and Lawrence J. Hirsch
Part VIII: The morbidity and mortality of epilepsy
33 mortality in Epilepsy 243 Elizabeth J. Donner
34 Accidents in Epilepsy 248 Allan Krumholz and Ana M. Sanchez
35 Medical Comorbidity in Epilepsy 253 Kimberly L. Pargeon and Sheryl R. Haut
36 Cognitive Effects of Chronic Epilepsy 260 Daniel L. Drane
37 Recognizing and Treating Psychiatric Comorbidity in Epilepsy 268 Jay Salpekar
Index 275
Color plate section between pages 80 and 81