Essential Biochemistry / Edition 3

by Charlotte W. Pratt, Kathleen Cornely

Overview

This new biochemistry text features a modern, chemical approach, always explaining the underlying chemistry of key biochemical molecules and reactions while taking advantage of recent developments. Features a true thematic and modern approach with a strong emphasis on research.

Product Details

ISBN-13:	9781118083505
Publisher:	Wiley
Publication date:	01/04/2013
Edition description:	New Edition
Pages:	744
Product dimensions:	8.60(w) x 11.10(h) x 1.20(d)

About the Author

Charlott Pratt received her Ph.D. in biochemistry from Duke University. She did post-doctoral research at the University of North Carolina at Chapel Hill and has contributed to numerous primary research articles and reviews. She is presently in the Department of Chemistry at Seattle Pacific University. She is co-author with Donald Voet and Judith Voet of Fundamentals of Biochemistry, also published by Wiley.

Kathleen Cornely received her Ph.D. in biochemistry from Cornell University. She has published numerous research articles and is presently Professor in the Department of Chemistry and Biochemistry at Providence College. She is a member of the Educational and Professional Development Committee of the American Society for Biochemistry and Molecular Biology and is on the editorial borad for the journal, Biochemistry and Molecular Biology Education.

Table of Contents

PART ONE: MOLECULAR STRUCTURE AND FUNCTION.
Chapter 1: The Chemical Basis of Life.
Chapter 2: Aqueous Chemistry.
Chapter 3: From Genes to Proteins.
Chapter 4: Myoglobin and Hemoglobin: A Study of Protein Structure and Function.
Chapter 5: Cytoskeletal and Motor Proteins.
Chapter 6: Chymotrypsin: A Model Enzyme.
Chapter 7: Enzyme Kinetics and Inhibition.
Chapter 8: Biological Membranes.
PART TWO: METABOLIC REACTIONS.
Chapter 9: Overview of Mammalian Metabolism and Free Energy.
Chapter 10: Glucose Metabolism.
Chapter 11: The Citric Acid Cycle.
Chapter 12: Oxidative Phosphorylation.
Chapter 13: Photosynthesis.
Chapter 14: Lipid Metabolism.
Chapter 15: Nitrogen Metabolism.
Chapter 16: Regulation of Mammalian Fuel Metabolism.
PART THREE: MANAGEMENT OF GENETIC INFORMATION.
Chapter 17: DNA Replication.
Chapter 18: Cancer and DNA Repair.
Chapter 19: Transcription and RNA.
Chapter 20: Protein Synthesis.

Editorial Reviews

Reviewer: Sophie La Salle, PhD (Midwestern University)
Description: This book presents an extensive and in-depth review of basic biochemical concepts by focusing on the framework that unites the chemistry and the biology of biochemistry. This edition stimulates active learning by using a question-based approach, a more dynamic presentation of the information, and additional web-based resources. The previous edition was published in 2010.
Purpose: It is intended to foster a solid foundation in modern biochemistry by providing students with practical knowledge and problem-solving skills. This important goal is achieved through the multifaceted learning approach adopted in this book.
Audience: It is written for undergraduate and graduate students in the biological sciences, but may be used by premedical, medical, and other healthcare graduate students as a thorough reference. Both editors have extensive research and teaching experience. Additionally, Dr. Pratt is coauthor of Fundamentals of Biochemistry: Life at the Molecular Level , 4th edition, Voet et al. (Wiley-Blackwell, 2013), while Dr. Cornely serves on the editorial board of Biochemistry and Molecular Biology Education.
Features: This book is divided into four major sections on foundations, molecular structure and function, metabolism and genetic information, each covering topics specifically related to modern biochemistry as it applies to human health, nutrition, and disease. This book is well organized, beautifully illustrated, and structured in a way that favors active learning. Features such as the "Do you remember?" section at the beginning of each chapter as well as "Key Concepts" and "Concept Review" firmly situate readers as they progress through each chapter. A dynamic question-based approach is also used: self-assessment questions are scattered throughout each chapter (e.g. within figures), at the end of each section as well as online. Sample calculations with practice problems are also included to help students develop their quantitative skills. Overall, this book is designed to provide students with a strong foundation in biochemistry through active learning rather than memorization.
Assessment: This is an elegant textbook that provides in-depth coverage of important basic biochemistry principles. It sets a solid foundation for concepts related to medical biochemistry. Readers looking for a quick review are best advised to choose another book. Compared to the previous edition, this edition includes up-to-date information on a number of topics, introduces new material emphasizing the connection between biochemistry and other fields, provides clinical connection boxes to explore the biochemical basis of diseases, and presents students with additional learning tools. Although breadth of coverage is not as extensive as in books such as Lehninger Principles of Biochemistry, 6th edition, Nelson and Cox (W.H. Freeman, 2013), or the aforementioned Fundamentals of Biochemistry, students may perceive this book as more approachable.

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