Essential Developmental Biology / Edition 3

Paperback (Print)
Rent
Rent from BN.com
$21.36
(Save 79%)
Est. Return Date: 10/20/2014
Used and New from Other Sellers
Used and New from Other Sellers
from $36.96
Usually ships in 1-2 business days
(Save 64%)
Other sellers (Paperback)
  • All (16) from $36.96   
  • New (9) from $54.51   
  • Used (7) from $36.96   

Overview

Essential Developmental Biology is a comprehensive, richly illustrated introduction to all aspects of developmental biology. Written in a clear and accessible style, the third edition of this popular textbook has been expanded and updated

In addition, an accompanying website - www.essentialdevelopmentalbiology.com- provides instructional materials for both student and lecturer use, including animated developmental processes, a photo gallery of selected model organisms, and all artwork in downloadable format.

With an emphasis throughout on the evidence underpinning the main conclusions, this book is an essential text for both introductory and more advanced courses in developmental biology.

Shortlisted for the Society of Biology Book Awards 2013 in the Undergraduate Textbook category.

Reviews of the Second Edition:

"The second edition is a must have for anyone interested in development biology. New findings in hot fields such as stem cells, regeneration, and aging should make it attractive to a wide readership. Overall, the book is concise, well structured, and illustrated. I can highly recommend it."
Peter Gruss, Max Planck Society

"I have always found Jonathan Slack's writing thoughtful, provocative, and engaging, and simply fun to read. This effort is no exception. Every student of developmental biology should experience his holistic yet analytical view of the subject."
Margaret Saha, College of William & Mary

Read More Show Less

Product Details

  • ISBN-13: 9780470923511
  • Publisher: Wiley
  • Publication date: 12/26/2012
  • Edition description: New Edition
  • Edition number: 3
  • Pages: 448
  • Sales rank: 863,126
  • Product dimensions: 8.50 (w) x 10.60 (h) x 0.90 (d)

Meet the Author

PROFESSOR JONATHAN SLACK has worked in London, Oxford and Bath and is currently Director of the Stem Cell Institute at the University of Minnesota, USA. He is a member of the European Molecular Biology Organization and a Fellow of the Academy of Medical Sciences. He has published numerous research papers on developmental biology as well as three other books, of which the most recent is Stem Cells: A Very Short Introduction.

Read More Show Less

Table of Contents

Preface, ix

About the companion website, xii

Section N: Groundwork, 1

N The excitement of developmental biology, 3

Where the subject came from, 3

Impact of developmental biology, 4

Future impact, 4

Further reading, 5

O How development works, 7

Ultrashort summary, 7

Gametogenesis, 10

Early development, 12

Morphogenetic processes, 19

Growth and death, 23

Further reading, 25

P Approaches to development: developmental genetics, 27

Developmental mutants, 27

Sex chromosomes, 29

Maternal and zygotic, 29

Genetic pathways, 29

Genetic mosaics, 32

Screening for mutants, 33

Cloning of genes, 34

Gain- and loss-of-function experiments, 34

Gene duplication, 38

Limitations of developmental genetics, 39

Further reading, 40

Q Approaches to development: experimental embryology, 42

Normal development, 42

Developmental commitment, 45

Criteria for proof, 51

Further reading, 52

R Approaches to development: cell and molecular biology techniques, 54

Microscopy, 54

Study of gene expression by molecular biology methods, 58

Study of gene expression by in situ methods, 61

Microinjection, 65

Cell-labeling methods, 66

Further reading, 68

Section O: Major model organisms, 71

S Model organisms, 73

The big six, 73

Access and micromanipulation, 75

Genetics and genome maps, 75

Relevance and tempo, 76

Other organisms, 76

Further reading, 78

T Xenopus, 80

Oogenesis, maturation, and fertilization, 80

Normal development, 82

Experimental methods, 87

Processes of regional specification, 92

Inductive interactions, 95

Further reading, 104

U The zebrafish, 106

Normal development, 106

Genetics, 110

Embryological and molecular techniques, 114

Regional specification, 115

Other uses for the zebrafish, 118

Further reading, 120

V The chick, 121

Normal development, 122

Regional specifi cation of the early embryo, 127

Description of organogenesis in the chick, 133

Further reading, 140

NM The mouse, 141

Mammalian fertilization, 141

Normal development, 145

Regional specifi cation, 153

Human early development, 158

Mouse developmental genetics, 159

Other topics in mouse development, 164

Further reading, 169

NN Drosophila, 171

Insects, 171

Normal development, 173

Drosophila developmental genetics, 178

The developmental program, 181

Further reading, 197

NO Caenorhabditis elegans, 198

Adult anatomy, 198

Embryonic development, 200

Analysis of postembryonic development, 208

Further reading, 215

Section 3: Organogenesis, 217

NP Techniques for studying organogenesis and postnatal development, 219

Genetics, 219

Clonal analysis, 223

Tissue and organ culture, 226

Cell separation methods, 228

Further reading, 230

NQ Development of the nervous system, 231

Overall structure and cell types, 231

Anteroposterior patterning of the neural plate, 234

Dorsoventral patterning of the neural tube, 238

Neurogenesis and gliogenesis, 240

The neural crest, 246

Development of neuronal connectivity, 250

Further reading, 257

NR Development of mesodermal organs, 259

Somitogenesis and myogenesis, 259

The kidney, 266

Germ cell and gonadal development, 269

Limb development, 274

Blood and blood vessels, 284

The heart, 287

Further reading, 293

NS Development of endodermal organs, 296

Normal development, 296

Experimental analysis of endoderm development, 301

The pancreas, 307

Further reading, 312

NT Drosophila imaginal discs, 314

Metamorphosis, 314

Disc development, 318

Further reading, 328

Section Q: Growth, regeneration, evolution, 331

NU Tissue organization and stem cells, 333

Types of tissue, 333

Tissue renewal, 336

Stem cells, 339

Further reading, 360

NV Growth, aging and cancer, 362

Growth: control of size and proportion, 362

Aging, 371

Cancer, 374

Further reading, 382

OM Regeneration of missing parts, 384

Distribution of regenerative capacity, 384

Planarian regeneration, 385

Insect limb regeneration, 388

Vertebrate limb regeneration, 390

General properties of regeneration, 399

Further reading, 400

ON Applications of pluripotent stem cells, 401

Cell transplantation therapy, 401

Embryonic stem cells, 403

Personalized pluripotent stem cells, 406

Proposed cell transplantation therapies using pluripotent stem cells, 411

Further reading, 417

OO Evolution and development, 419

Macroevolution, 420

The primordial animal, 424

What really happened in evolution?, 429

Further reading, 438

Appendix: Key molecular components, 440

Genes, 440

Transcription factor families, 442

Signaling systems, 443

Inducing factor families, 445

Cytoskeleton, 449

Cell adhesion molecules, 451

Extracellular matrix components, 452

Further Reading, 452

Glossary, 454

Index, 467

Read More Show Less

Customer Reviews

Average Rating 2
( 1 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(1)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously
Sort by: Showing 1 Customer Reviews
  • Anonymous

    Posted February 20, 2014

    No text was provided for this review.

Sort by: Showing 1 Customer Reviews

If you find inappropriate content, please report it to Barnes & Noble
Why is this product inappropriate?
Comments (optional)