Estrogen and Breast Cancer

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Overview

Breast cancer is the most common female malignancy. This book reviews the evidence that estrogens are a major influence of risk to and growth of breast cancer. The book indicates how the breast and its tumors may obtain estrogen from different sources and display distinctive patterns and levels of estrogen. It also illustrates how increasing knowledge of the mechanism of estrogen action is leading to new strategies for not only women with breast cancer but also those at high ...

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More About This Book

Overview

Breast cancer is the most common female malignancy. This book reviews the evidence that estrogens are a major influence of risk to and growth of breast cancer. The book indicates how the breast and its tumors may obtain estrogen from different sources and display distinctive patterns and levels of estrogen. It also illustrates how increasing knowledge of the mechanism of estrogen action is leading to new strategies for not only women with breast cancer but also those at high risk for the disease.

The book contains black-and-white illustrations.

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Editorial Reviews

Booknews
Focuses on the twin themes of involvement of estrogen hormones in the development of the normal breast, and of the evidence that both exogenous and endogenous estrogens influence carcinogenesis within the breast and the behavior of established cancers. Discusses effects on tumor behavior, sources of estrogen and sites of biosynthesis, levels and patterns within breast fluids and tissues, mechanisms of action, endocrine therapy, predicting sensitivity and dependence, and future perspectives. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Product Details

  • ISBN-13: 9780412103711
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 1/28/1996
  • Series: Medical Intelligence Unit Series
  • Edition number: 1
  • Pages: 207

Table of Contents

1 Introduction 1
2 Estrogens and the Normal Breast 25
3 Estrogens and the Risk of Breast Cancer 35
4 Estrogen and Tumor Behavior 63
5 Sources of Estrogen and Sites of Biosynthesis 75
6 Levels and Patterns of Estrogen Within the Breast, Its Fluids and Tissues 95
7 Mechanism of Estrogen Action 111
8 Estrogen and Endocrine Therapy for Breast Cancer 125
9 Prediction of Estrogen Sensitivity/Dependence 151
10 Estrogen Independence 171
11 Future Perspectives 197
Index 205
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