Evaluation of Certain Food Additives and Contaminants: Seventy-fourth Report of the Joint FAO/WHO Expert Committee on Food Additives

by World Health Organization

Overview

This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of various food additives, with a view to recommending acceptable daily intakes (ADIs) and to preparing specifications for identity and purity. The Committee also evaluated the risk posed by two food contaminants, with the aim of deriving tolerable intakes where appropriate and advising on risk management options for the purpose of public health protection.

The first part of the report contains a general discussion of the principles governing the toxicological evaluation of and assessment of dietary exposure to food additives and contaminants. A summary follows of the Committee's evaluations of technical, toxicological and dietary exposure data for certain food additives (aluminium-containing food additives, Benzoe Tonkinensis, glycerol ester of gum rosin, glycerol ester of tall oil rosin, glycerol ester of wood rosin, octenyl succinic acid modified gum arabic, polydimethyl siloxane, Ponceau 4R, pullulan, pullulanase from Bacillus deramificans expressed in Bacillus licheniformis, Quinoline Yellow and Sunset Yellow FCF) and two food contaminants (cyanogen glycosides and fumonisins).

Specifications for the following food additives were revised: aluminium lakes of colouring matters; B-apo-8'-carotenal; B-apo-8'-carotenoic acid ethyl ester; B-carotene, synthetic; hydroxypropyl methyl cellulose; magnesium silicate, synthetic; modified starches; nitrous oxide; sodium carboxymethyl cellulose; and sucrose monoesters of lauric, palmitic or stearic acid. Annexed to the report are tables summarizing the Committee's recommendations for dietary exposures to and toxicological evaluations of the food additives and contaminants considered.

Product Details

ISBN-13:	9789241209663
Publisher:	World Health Organization
Publication date:	08/28/2012
Series:	WHO Technical Report Series , #966
Pages:	114
Product dimensions:	6.10(w) x 9.40(h) x 0.40(d)

About the Author

World Health Organization is a Specialized Agency of the United Nations, charged to act as the world's directing and coordinating authority on questions of human health. It is responsible for providing leadership on global health matters, shaping the health research agenda, setting norms and standards, articulating evidence-based policy options, providing technical support to countries, and monitoring and assessing health trends.

Table of Contents

412 2.3 Principles governing t

413 2.3.1 The use of P-values as an exclusion criterion for the selection of BMDLs derived by benchmark dose model

512 2.4 Food additive specifications 513 2.4.1 Request from C

513 2.4.2 Methods for analysis of propylene chlorohydrins 613 2.4.3

614 2.4.

Potassium bromate 612 2.5 General comment on data submissions 611 3 Specific f

712 3.1 Safety evaluations 713 3.1.1 Alu

713 3.1

Benzoe Tonkinensis 1813 3.1

Glycerol ester of gum rosin 2113 3.1.4 G

2

3.1.5 Glycerol ester of

2513 3.1.6 Octenyl succinic acid mo

2713 3.1.7 P

2713 3.1.8 Ponceau

3213 3.1.9 Pullulan 3613 3.1.10 Pull

4013 3.1.11 Quinoline Yell

4313 3.1.12 Sunset Yellow FCF

3.2 Revision of s

5013 3.

β-Apo-8'-carotenal 5013 3.2.2 β-Apo-8'-carotenoic acid ethyl ester 501

3.2.3 β-Carotene, synthe

5013 3.2.4 Hydroxypropyl m

5113 3.2.5 Magnesium

5113 3.2.6 Mod

5113 3.2.7 Nitrous oxide 5213 3.2.8

Sodium carboxymethyl cellulose 5213 3

Sucrose monoesters of lauric, palmitic o

5212 3.3 Revision of metho

5213 3.3.1 Method for colo

5211 4 Contaminants 5512

Cyanogenic glycosides 5512 4.2 Fumonisins 7011 5 Future w

9511 6 Recommendations 9

Acknowledgement 9901 References 10101 Annex 1 Reports and ot

10

Annex 2 Acceptable o

12301 Annex 3 Further information required or desired 133