Evidence-Based Diagnosis

Evidence-Based Diagnosis

by Thomas B. Newman, Michael A. Kohn
     
 

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ISBN-10: 052188652X

ISBN-13: 9780521886529

Pub. Date: 02/16/2009

Publisher: Cambridge University Press

Evidence-Based Diagnosis is a textbook about diagnostic, screening, and prognostic tests in clinical medicine. The authors' approach is based on many years of experience teaching physicians in a clinical research training program. Although requiring only a minimum of mathematics knowledge, the quantitative discussions in this book are deeper and more rigorous than

Overview

Evidence-Based Diagnosis is a textbook about diagnostic, screening, and prognostic tests in clinical medicine. The authors' approach is based on many years of experience teaching physicians in a clinical research training program. Although requiring only a minimum of mathematics knowledge, the quantitative discussions in this book are deeper and more rigorous than those in most introductory texts. The book includes numerous worked examples and 60 problems (with answers) based on real clinical situations and journal articles. The book will be helpful and accessible to anyone looking to select, develop, or market medical tests. Topics covered include:

Product Details

ISBN-13:
9780521886529
Publisher:
Cambridge University Press
Publication date:
02/16/2009
Pages:
312
Product dimensions:
7.20(w) x 10.00(h) x 0.90(d)

Table of Contents

Preface vii

Acknowledgments & Dedication ix

Abbreviations/Acronyms xi

1 Introduction: understanding diagnosis and diagnostic testing 1

2 Reliability and measurement error 10

3 Dichotomous tests 39

4 Multilevel and continuous tests 68

5 Critical appraisal of studies of diagnostic tests 94

6 Screening tests 116

7 Prognostic tests and studies 138

8 Multiple tests and multivariable decision rules 156

9 Quantifying treatment effects using randomized trials 186

10 Alternatives to randomized trials for estimating treatment effects 206

11 Understanding P-values and confidence intervals 220

12 Challenges for evidence-based diagnosis 239

Answers to problems 255

Index 287

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