Evidence-Based Medical Monitoring: From Principles to Practice / Edition 1

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Monitoring is a major component of management of chronic diseases such as diabetes, cardiovascular disease, arthritis and depression. Yet poor monitoring means healthcare costs are rising.

This book discusses how monitoring principles adopted in other spheres such as clinical pharmacology and evidence-based medicine can be applied to chronic disease in the global setting. With contributions from leading experts in evidence-based medicine, it is a ground-breaking text for all involved in delivery of better and more effective management of chronic illnesses.

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Editorial Reviews

Doody's Review Service
Reviewer: Vincent F Carr, DO, MSA, FACC, FACP (Uniformed Services University of the Health Sciences)
Description: The vast majority of current research concerns new therapeutic modalities. This book looks at a relatively little discussed, but equally important, concept of how chronic conditions are monitored. Most interesting is the discussion concerning the available evidence upon which to base monitoring decisions.
Purpose: The author presents an authoritative consideration of the principles of monitoring chronic conditions and the success of therapeutic interventions. Considering the cost of both the therapeutics and the monitoring modalities, this goal of asking what we are doing is most important and the authors have given us a unique and easily understandable thought process to evaluate our habits.
Audience: This is a highly useful approach for students learning and forming their practice habits and also for experienced attending clinicians who may wish to reconsider their approach to chronic care. The authors are seasoned professors who have the experience to both question the common wisdom and show a new way to monitoring patients.
Features: The book takes one through the thought process of why monitoring testing is performed, emphasizing the principles of testing based upon proper timing, physiology, and the potential for changing therapy. They make an excellent case that monitoring in the acute or after changes stage is different that the chronic stage when stability is anticipated. Chapters also cover very practical situations such as diabetes, chronic anticoagulation, and transplantation and intensive care medicine. The references are very good and the index complete.
Assessment: Simply stated, this should be mandatory reading for medical students, perhaps the basis for an entire course of study in medical school, and somehow periodic reading for clinicians in practice. The book is that valuable!
From the Publisher
"Evidenced-based Medical Monitoring would be valuable addition to academic and health sciences library collections and is therefore highly recommended." (E-Streams, December 2008)

“This should be mandatory reading for medical students, perhaps the basis for an entire course of study … .The book is that valuable!” (Doody's Book Reviews)

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Product Details

  • ISBN-13: 9781405153997
  • Publisher: Wiley
  • Publication date: 2/8/2008
  • Series: Evidence-Based Medicine Series
  • Edition number: 1
  • Pages: 376
  • Product dimensions: 6.00 (w) x 9.10 (h) x 0.80 (d)

Meet the Author

Professor Paul Glasziou, University of Oxford, Department of Primary Health Care and Director of the Centre for Evidence-based Medicine, Oxford. Paul is a leading figure in evidence-based medicine. He teaches courses and organises workshops both at the Centre in Oxford and the other centres around the world (eg McMaster, Bond University- Australia).

Les Irwig, Professor in the School of Public Health, University of Sydney He teaches courses on diagnostic test assessment, meta-analysis and guideline development, and advanced epidemiological methods. He is especially interested in the application of epidemiological methods to provide the evidence on which to base public health and clinical decisions.

Dr Jeffery Aronson, Clinical Reader in Pharmacology, University of Oxford, UK.

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Table of Contents


Part 1 The Theory of Monitoring.


1 An introduction to monitoring therapeutic interventions in clinical practice (Paul P. Glasziou, University of Oxford; Jeffrey K. Aronson, University of Oxford).

2 A framework for developing and evaluating a monitoring strategy (David Mant, University of Oxford).


3 Developing monitoring tools: integrating the pathophysiology of disease and the mechanisms of action of therapeutic interventions (Jeffrey K. Aronson, University of Oxford; Susan Michie, University College London).

4 Biomarkers and surrogate endpoints in monitoring therapeutic interventions (Jeffrey K. Aronson, University of Oxford).

5 Choosing the best monitoring tests (Les Irwig, University of Sydney; Paul P. Glasziou, University of Oxford).


6 Monitoring the initial response to treatment (Katy Bell, University of Sydney; Jonathan Craig, University of Sydney; Les Irwig, University of Sydney).

7 Control charts and control limits in long-term monitoring (Petra Macaskill, University of Sydney).

8 Developing a monitoring schedule: frequency of measurement (Andrew J. Farmer, University of Oxford).

9 How should we adjust treatment? (Paul P. Glasziou, University of Oxford).


10 Monitoring as a learning and motivational tool (Susan Michie, University College London; Kirsten McCaffery, University of Sydney); Carl Heneghan, University of Oxford).

11 Monitoring from the patient's perspective: the social and psychological implications (Kirsten McCaffery, University of Sydney; Susan Michie, University College London).


12 Evaluating the effectiveness and costs of monitoring (Patrick M.M. Bossuyt, University of Amsterdam).

13 Good practice in delivering laboratory monitoring (W. Stuart A. Smellie, Bishop Auckland Hospital, County Durham).

14 Point-of-care testing in monitoring (Christopher P. Price, University of Oxford).

15 Monitoring for the adverse effects of drugs (Jamie J. Coleman, Queen Elizabeth Hospital, Birmingham; Robin E. Ferner, City Hospital, Birmingham; Jeffrey K. Aronson, University of Oxford).

Part 2 The Practice of Monitoring.

16 Monitoring diabetes mellitus across the lifetime of illness (Andrew J. Farmer, University of Oxford).

17 Oral anticoagulation therapy (OAT) (Carl Heneghan, University of Oxford; Rafael Perera, University of Oxford).

18 Monitoring cholesterol-modifying interventions (Paul P. Glasziou, University of Oxford; Les Irwig, University of Sydney; Stephane Heritier, (University of Sydney).

19 Monitoring levothyroxine replacement in primary hypothyroidism (Andrea Rita Horvath, University of Szeged).

20 Monitoring in renal transplantation (Nicholas B. Cross, University of Sydney; Jonathan Craig, University of Sydney).

21 Monitoring in pre-eclampsia (Pisake Lumbiganon, Khon Kaen University; Malinee Laopaiboon, Khon Kaen University).

22 Monitoring in intensive care (Jan M. Binnekade, University of Amsterdam; Patrick M.M. Bossuyt, University of Amsterdam).

23 Monitoring intraocular pressure in glaucoma (Les Irwig, University of Sydney; Paul R. Healey, University of Sydney; Jefferson D’Assunşăo, University of Sydney; Petra Macaskill, University of Sydney).

24 Monitoring in osteoarthritis (George Peat, Keele University; Mark Porcheret, Keele University; John Bedson, Keele University; Alison M. Ward, University of Oxford).


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