Evolution after Gene Duplication [NOOK Book]

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Overview

Gene duplication has long been believed to have played a major role in the rise of biological novelty through evolution of new function and gene expression patterns. The first book to examine gene duplication across all levels of biological organization, Evolution after Gene Duplication presents a comprehensive picture of the mechanistic process by which gene duplication may have played a role in generating biodiversity.

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Evolution after Gene Duplication

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Overview

Gene duplication has long been believed to have played a major role in the rise of biological novelty through evolution of new function and gene expression patterns. The first book to examine gene duplication across all levels of biological organization, Evolution after Gene Duplication presents a comprehensive picture of the mechanistic process by which gene duplication may have played a role in generating biodiversity.

Key Features:

  • Explores comparative genomics, genome evolution studies and analysis of multi-gene families such as Hox, globins, olfactory receptors and MHC (immune system)
  • A complete post-genome treatment of the topic originally covered by Ohno's 1970 classic, this volume extends coverage to include the fate of associated regulatory pathways
  • Taps the significant increase in multi-gene family data that has resulted from comparative genomics
  • Comprehensive coverage that includes opposing theoretical viewpoints, comparative genomics data, theoretical and empirical evidence and the role of bioinformatics in the study of gene duplication

This up-to-date overview of theory and mathematical models along with practical examples is suitable for scientists across various levels of biology as well as instructors and graduate students.

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Editorial Reviews

From the Publisher

"This up-to-date overview of theory and mathematical models along with practical examples is suitable for scientists across various levels of biology as well as instructors and graduate students." (Forbes.com, 27 October 2010)

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Product Details

  • ISBN-13: 9781118148099
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 6/9/2011
  • Sold by: Barnes & Noble
  • Format: eBook
  • Edition number: 1
  • Pages: 350
  • File size: 8 MB

Table of Contents

Contributors

Preface

1 Understanding Gene Duplication Through Biochemistry and Population Genetics 1

2 Functional Divergence of Duplicated Genes Katharina Dittmar Dittmar, Katharina 23

3 Duplicate Retention After Small- and Large-Scale Duplications Aoife McLysaght McLysaght, Aoife 31

4 Gene Dosage and Duplication Yves Van de Peer Van de Peer, Yves 57

5 Myths and Realities of Gene Duplication Fyodor A. Kondrashov Kondrashov, Fyodor A. 77

6 Evolution After and Before Gene Duplication? Robert Friedman Friedman, Robert 105

7 Protein Products of Tandem Gene Duplication: A Structural View Erich Bornberg-Bauer Bornberg-Bauer, Erich 133

8 Statistical Methods for Detecting Functional Divergence of Gene Families Michael I. Sadowski Sadowski, Michael I. 163

9 Mapping Gene Gains and Losses Among Metazoan Full Genomes Using an Integrated Phylogenetic Framework Xun Gu Xun, Gu 173

10 Reconciling Phylogenetic Trees Michel C. Milinkovitch Milinkovitch, Michel C. 185

11 On the Energy and Material Cost of Gene Duplication David A. Liberles Liberles, David A. 207

12 Fate of a Duplicate in a Network Context Andreas Wagner Wagner, Andreas 215

13 Evolutionary and Functional Aspects of Genetic Redundancy Orkun S. Soyer Soyer, Orkun S. 229

14 Phylogenomic Approach to the Evolutionary Dynamics of Gene Duplication in Birds Tzachi Pilpel Pilpel, Tzachi 253

15 Gene and Genome Duplications in Plants Scott V. Edwards Edwards, Scott V. 269

16 Whole Genome Duplications and the Radiation of Vertebrates Douglas E. Soltis Soltis, Douglas E. 299

Index Axel Meyer Meyer, Axel 313

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