Exercise and Intracellular Regulation of Cardiac and Skeletal Muscle / Edition 1

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Overview

This book examines the effects of acute and chronic exercise on the metabolism of cyclic AMP and protein kinase in cardiac and skeletal muscle. Written by four of the world leaders in this emerging area of exercise biochemistry, Exercise and Intracellular Regulation of Cardiac and Skeletal Muscle also presents information gained during more than 20 years of work in the Soviet Union.

Michael Kalinski directed groundbreaking work at the Kiev State Institute of Physical Culture and the Kiev Research Institute of Biochemistry, two institutes known for establishing new frontiers in exercise biochemistry. In this book, he shares the results of his studies there in the areas of hormonal and intracellular regulation of metabolism.

The book is divided into three parts. Part I provides a comprehensive review of the role of phosphorylation in the functional regulation of cardiac and skeletal muscle. Part II presents new information describing the effects of exercise on cAMP and cAMP-dependent protein kinase. Part III summarizes this information.

This monograph is an excellent reference for exercise biochemists and exercise physiologists. "Non-exercise" biochemists and physiologists who want to fully understand cardiac and skeletal muscle physiology and biochemistry will also find this to be a helpful source.

Exercise and Intracellular Regulation of Cardiac and Skeletal Muscle is the seventh volume in the HK Sport Science Monograph Series.

The book contains black-and-white illustrations.

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Editorial Reviews

Booknews
This is the first English translation of 20 years of Soviet research into the effects of exercise on cyclic AMP (cAMP) and cAMP-dependent protein kinase. The researchers examine phosphorylation and the functional regulation of cardiac and skeletal muscle, and the effects of acute and chronic exercise on the metabolism of cAMP and protein kinase in cardiac and skeletal muscle, focusing on the compartmentalization of second messengers. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Product Details

  • ISBN-13: 9780873227254
  • Publisher: Human Kinetics Publishers
  • Publication date: 5/2/1995
  • Series: Sport Science Monograph Series , #7
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 96
  • Product dimensions: 6.02 (w) x 8.98 (h) x 0.25 (d)

Table of Contents

HK Sport Science Monograph Series
Preface
Acknowledgments

Part I: Phosphorylation and the Functional Regulation of Cardiac and Skeletal Muscle
Chapter 1.
Phosphorylation of Cell Membrane Calcium Channel Proteins
Calcium Channel Proteins in Cardiac Muscle
Calcium Channel Proteins in Skeletal Muscle
Calcium ATPase and Sodium-Calcium Carrier

Chapter 2. cAMP-Dependent Phosphorylation of Sarcoplasmic Reticulum Proteins
Phosphorylation of Myocardial Phospholamban
Phosphorylation in Slow and Fast Skeletal Muscle

Chapter 3. Myofibrillar Protein Phosphorylation
Troponin
Other Substrates

Part II: The Effects of Exercise on cAMP Metabolism and Properties of cAMP-Dependent Protein
Kinase of Cardiac and Skeletal Muscle

Chapter 4. Exercise, cAMP, and cAMP-Dependent Protein Kinase in Cardiac Muscle cAMP Metabolism cAMP-Dependent Protein Kinase

Chapter 5. Effects of Prolonged Exercise and Training on Skeletal Muscle cAMP and cAMP-Dependent Protein Kinase cAMP Metabolism cAMP-Dependent Protein Kinase

Part III: Summary
Chapter 6. Present Understanding of the cAMP System in the Adaptations of Muscle to Exercise
Compartmentalization of Second Messengers
Significance of Changes in cAMP-Dependent Phosphorylation

References

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