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Exercise-Induced Acute Renal Failure: Acute Renal Failure with Severe Loin Pain and Patchy Renal Ischemia after Anaerobic Exercise / Edition 1
     

Exercise-Induced Acute Renal Failure: Acute Renal Failure with Severe Loin Pain and Patchy Renal Ischemia after Anaerobic Exercise / Edition 1

by Isao Ishikawa
 

ISBN-10: 4431694838

ISBN-13: 9784431694830

Pub. Date: 06/05/2007

Publisher: Springer Japan

Acute renal failure induced by rhabdomyolysis after strenuous, prolonged exercise such as marathon running or mountain climbing is a well-known medical phenomenon, but exercise-induced acute renal failure after short-term anaerobic exercise - for instance, short-distance track races - has been recognized only recently. This monograph provides in-depth information

Overview

Acute renal failure induced by rhabdomyolysis after strenuous, prolonged exercise such as marathon running or mountain climbing is a well-known medical phenomenon, but exercise-induced acute renal failure after short-term anaerobic exercise - for instance, short-distance track races - has been recognized only recently. This monograph provides in-depth information on exercise-induced acute renal failure after short-term anaerobic exercise, which causes severe pain in the loin and patchy renal ischemia with no sign of rhabdomyolysis. Half of the patients suffering from this condition experience renal hypouricemia, for which approximately 20% are treated with dialysis. This complete clinical reference book includes characteristics of the disease, diagnosis, treatment and prognosis, and corresponding preventive measures. Important information on gene analysis and etiology is also included, creating a valuable resource for nephrologists as well as for emergency physicians and those in the field of sports medicine.

Product Details

ISBN-13:
9784431694830
Publisher:
Springer Japan
Publication date:
06/05/2007
Edition description:
2007
Pages:
108
Product dimensions:
7.01(w) x 10.00(h) x 0.02(d)

Table of Contents

Chapter 1. Exercise related acute renal failure

(1)Description regarding exercise related acute renal failure

(2) Myoglobinuria-related/non-myoglobinuria-related acute renal failure

Chapter 2. Exercise-induced acute renal failure (ALPE)

(1) The first patient in whom wedge-shaped patchy renal ischemia was demonstrated

(2) Our series in the initial phase

Chapter 3. Wedge–shaped patchy renal ischemia

(1) Visualization of residual contrast medium on delayed CT with respect to the interval from administration of contrast medium (assessment of regional kidney function)

(2) Interpretation of wedge-shaped renal lesions

(3) Administration of contrast medium in the presence of acute renal failure

(4) Visualization of wedge-shaped lesions by bone scan with MDP and MRI

Chapter 4. Definition of exercise-induced acute renal failure (ALPE)

(1) Criteria for typical ALPE:

(2) Non-typical cases

Chapter 5. Our series (22 patients)

(1)Patient characteristics

(2)Delayed CT, MRI, and bone scan with MDP

(3)Kidney biopsy

Chapter 6. Summary of 155 patients collected from the literature

(1) Background

(2) Findings on the initial consultation and laboratory data

(3) Renal hypouricemia

(4)Imaging findings (wedge-shaped patchy renal ischemia)

(5)Kidney biopsy

(6)Relapse

Chapter 7. Exercise

(1)Type of exercise

(2)Anaerobic exercise

(3)Involvement of type II muscle fibers

Chapter 8. Loin pain

(1) Timing of onset and duration

(2) Sites and features of pain

(3) Mechanism involved in pain

Chapter 9. Renal hypouricemia

(1)Serum creatinine and uric acid levels

(2) Comparison of patients with and without renal hypouricemia

(3) Reasons for a high incidence of ALPE in patients with renal hypouricemia

(4) Reason why patients with renal hypouricemia frequently develop ALPE and its mechanism

Chapter 10. Gene analysis of uric acid transporter (URAT1)

(1) URAT1 gene analysis in patients with renal hypouricemia who developed ALPE

Chapter 11. Risk factors other than renal hypouricemia

(1)Exercise in the presence of a cold

(2)Administration of antipyretic analgesic agents before exercise

(3)Exercise in the presence of dehydration

Chapter 12. Etiology/pathogenesis

(1) Hypothesis regarding the development of exercise-induced acute renal failure (ALPE)

(2) Investigation of serum specific markers (SDS-PAGE, proteomics)

(3) Investigation of oxidative stress markers

(4)Exercise load test

(5) Preparation of wedge-shaped patchy renal ischemia in an animal experiment

(6) Verification of hypotheses

Chapter 13. Diagnosis

(1) Initially suspected disorders

(2) Diagnosis of ALPE

(3) Differentiation of ALPE from myoglobinuria-related acute renal failure

(4) Necessity of visualizing wedge-shaped patchy renal ischemia

Chapter 14. Treatment

(1) Treatment

(2) Cautions

Chapter 15. Course and prognosis

(1) Interval required until improvement in kidney function

(2) Prognosis, patients undergoing hemodialysis

Chapter 16. Prevention

(1)Preventive methods

(2)Cautions for elementary and junior/senior high schools

Chapter 17. Conclusion

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