The Fetal Matrix: Evolution, Development and Disease

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New discoveries reveal how crucial interactions that determine our destiny occur before birth, when our genes interact with their environment as the embryo and fetus develop. The new concepts in this book are crucial to understanding the public health burden in societies undergoing rapid transition from poverty to affluence. They add an important new dimension to evolutionary theory. Synthesising developmental biology, evolutionary history, medical science, public health and social policy, this is a ground-breaking account by two of the world's leading pioneers in this emerging field.
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Editorial Reviews

From the Publisher
"The authors are persuasive and their findings have relevance for health policy everywhere"
New Scientist

"...a detailed and comprehensive account...highly readable with many interesting examples provided to illuminate key points of the author's thesis...I recommend this book highly as a contribution to the growing literature on developmental plasticity, genomic regulation and human adaptive physiological processes."
The Midwest Book Review, A.R. Cellura, Ed. D.

"Despite the complexity of the topic, the authors have managed a tour de force in making it understandable to the educated lay reader as well as the specialized professional."
Nicole J. Bernshaw, MSc, IBCLC, Official Journal of the International Lactation Consultant Association

"The biological interpretation of disease and health is a topic in need of serious attention and wider dissemination. In The Fetal Matrix, Gluckman and Hanson have made a very interesting contribution to this enterprise."
Stephen Lewis

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Product Details

  • ISBN-13: 9780521834575
  • Publisher: Cambridge University Press
  • Publication date: 9/15/2004
  • Pages: 268
  • Product dimensions: 6.85 (w) x 9.72 (h) x 0.75 (d)

Meet the Author

In 2004, Dr Peter Gluckman was named 'New Zealander of the Year' by the New Zealand Herald. The newspaper recognized him for 'a long career of achievement that has brought life-saving developments in medicine and demonstrated an ability to produce world-leading scientific research in New Zealand.
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Table of Contents

1 Shaping our destiny : genes, environment and their interactions 1
2 Mother and fetus 25
3 Fetal choices 59
4 Predictive adaptive responses and human disease 78
5 Obesity, diabetes and other diseases 103
6 The biology of predictive adaptive responses 118
7 Predictive adaptive responses - critical processes in evolution 144
8 Evolutionary echoes and the human camel 173
9 Improving human health 190
10 Fetal futures 206
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