Fibrinogen, Thrombosis, Coagulation, and Fibrinolysis

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Product Details

  • ISBN-13: 9781461366973
  • Publisher: Springer US
  • Publication date: 12/31/2013
  • Series: Advances in Experimental Medicine and Biology Series, #281
  • Edition description: Softcover reprint of the original 1st ed. 1990
  • Pages: 450
  • Product dimensions: 6.69 (w) x 9.61 (h) x 0.94 (d)

Table of Contents

Native Fibrin Gel Networks and Factors Influencing their Formation in Health and Disease.- The Structure and Evolution of Vertebrate Fibrinogen: A Comparison of the Lamprey and Mammalian Proteins.- Nucleotide Sequences of the Three Genes Coding for Human Fibrinogen.- On the Identity of Fibrin(ogen) Oligomers Appearing During Fibrin Polymerization.- Immunochemical Studies of A? Chain Crosslinking.- Abnormal Fibrinogens with Two Structural Defects.- Electrophoretic Characterizations of Cross-Linked Fibrinogen Derivatives in Blood and Vascular Tissue by Zonal Immobilization on Glyoxyl Agarose.- Studies on the Localization and Accessibility of Sites in Fibrin which Are Involved in the Acceleration of the Activation of Plasminogen by Tissue-Type Plasminogen Activator.- Prothrombinase: Recognition and Developments.- The Initiation of the Tissue Factor Dependent Pathway of Blood Coagulation.- Interactions Between the Contact System, Neutrophils and Fibrinogen.- A New Trisaccharide Sugar Chain Linked to a Serine Residue in the First EGF-Like Domain of Clotting Factors VII and IX and Protein Z.- Multiple Epitope Specificity of Monoclonal Antibodies to a Single Synthetic Peptide: Use in the Characterization of the GP lIb-IIIa Binding Domain of von Willebrand Factor.- Factor VII and Dietary Fat Intake.- Characterization of Snake Venom Principles Affecting Blood Coagulation and Platelet Aggregation.- Thrombin-Like Venom Enzymes: Structure and Function.- Thrombin Inhibition by Synthetic Hirudin Peptides.- Effects of Structural Modifications on the Properties of Tissue Plasminogen Activator (tPA).- Molecular Genetics of Alpha 2 Plasmin Inhibitor.- Biological Properties of Hybrid Plasminogen Activators.- The Regulation of the Activaton of the Fibrinolysis System.- The Mechanisms of the Activation of Plasminogen by Streptokinase and Urokinase.- Protein C and Fibrinolysis: A Link Between Coagulation and Fibrinolysis.- Transformation of Prostacyclin (PGI2) to a Biologically Active Metabolite: 5(6)-Oxido-PGI1 by Cyhrome P450-Dependent Epoxygenase.- Studies on the Localization of Fibrinogen Binding Sites on Platelet Glycoprotein IIIa.- Affinity Labeling of Nucleotide Binding Sites of Enzymes and Platelets.- The Effect of Ganodermic Acid S on Human Platelets.- Role of Insulin Receptors in the Expression of Prostaglandin E1 Binding Activity in Platelets.- Platelet-Fibrin Interaction in the Suspension and Under Flow Conditions.- An Independent Haemostatic Mechanism: Shear Induced Platelet Aggregation.- Regulation of Eicosanoid Biosynthesis in Endothelial Cells: Critical Role of De Novo Synthesis of Prostaglandin Endoperoxide Synthase.- Modulation of Endothelial Function by Hypoxia: Perturbation of Barrier and Anticoagulant Function, and Induction of a Novel Factor X Activator.- Fibrin and the Vessel Wall.- Interactions between Fibrin, Collagen and Endothelial Cells in Angiogenesis.- New Developments in Thrombolytic Therapy.- Coronary Thrombosis: Pathogenesis and Prevention.- Implications of the TIMI Trials.- Thrombotic Microangiopathy.- Clinical Trials with Alteplase (RT-pa) in Acute Myocardial Infarction.- The Effects of Streptokinase and Tissue Plasminogen Activator on Left Ventricular Function.- Modern Strategies for Treatment of Acute Myocardial Infarction: Significance of Haemostaseological and Rheological Findings.- Clinical Application of Tissue Plasminogen Activator Therapy in Acute Myocardial Infarction.- Fibrinogen Proteolysis and Coagulation System Activation During Thrombolytic Therapy.- Altered Rheological Properties of Blood Following Administrations of Tissue Plasminogen Activator and Streptokinase in Patients with Acute Myocardial Infarction.- Monoclonal Antibodies for the Detection of Thrombosis.- The Pharmacology and Clinical Pharmacology of Defibrotide: A New Profibrinolytic, Antithrombotic, and Anti-Platelet Substance.- Author Index.

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